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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 84289 |
Name | ING5 |
Synonym | p28ING5;inhibitor of growth family, member 5;ING5;inhibitor of growth family, member 5 |
Definition | inhibitor of growth protein 5 |
Position | 2q37.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
Evidence Status | Description |
potential | "ING5 may function as a tumor suppressor gene or oncogene tightly linked with p53 status, and may play an important role in the prognosis of head and neck squamous cell carcinoma (HNSCC) patients." |
reviewed | Tumor-specific mutation and down-regulation of ING5 mRNA suggested it as a tumor suppressor gene in oral squamous cell carcinoma. |
reviewed | ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. |
| More detail of all 3 literatures about ING5 | |
External Links | |
Links to Entrez Gene | 84289 |
Links to all GeneRIF Items | 84289 |
Links to iHOP | 84289 |
Sequence Information | |
Nucleotide Sequence | >84289 : length: 723 atggcgaccgccatgtacttggagcactatctggacagtatcgagaaccttccctgcgaa cttcagaggaacttccagctgatgcgagagctggaccagaggacggaagataagaaagca gagattgacatcctggctgcagagtacatctccacggtgaagacgctgtctccagaccag cgcgtggagcgcctgcagaagatccagaacgcctacagcaagtgcaaggaatacagtgac gacaaagtgcagctggccatgcagacctacgagatggtggataaacacattcgaaggctt gatgcagacctggcgcgctttgaagcagatctgaaggacaagatggagggcagtgatttt gaaagctccggagggcgagggttaaaaaaaggccggggtcagaaagaaaaaagagggtcc cggggccgaggcaggaggacatcagaggaagacacaccaaagaaaaagaagcacaaagga gggtctgagttcactgacaccatcctgtccgtgcacccctctgatgtgctggacatgccc gtggacccaaacgaacccacgtactgcctgtgccaccaggtctcctatggggagatgatt ggctgtgacaatccagactgtccaattgagtggtttcactttgcctgcgtggaccttacc acgaaacccaaaggaaaatggttctgtccacggtgtgtccaggaaaagaggaagaagaag tag |
Protein Sequence | >84289 : length: 240 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDF ESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMP VDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK |