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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 84295 |
Name | PHF6 |
Synonym | BFLS|BORJ|CENP-31;PHD finger protein 6;PHF6;PHD finger protein 6 |
Definition | PHD-like zinc finger protein|centromere protein 31 |
Position | Xq26.3 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | PHF6 as a tumor suppressor gene mutated in acute myeloid leukemias (AML) and extend the role of this X-linked tumor suppressor gene in the pathogenesis of hematologic tumors. |
reviewed | these results identify PHF6 as a new X-linked tumor suppressor in T-ALL and point to a strong genetic interaction between PHF6 loss and aberrant expression of TLX transcription factors in the pathogenesis of this disease. |
| More detail of all 2 literatures about PHF6 | |
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External Links |
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Links to Entrez Gene | 84295 |
Links to all GeneRIF Items | 84295 |
Links to iHOP | 84295 |
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Sequence Information |
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Nucleotide Sequence |
>84295 : length: 1098 atgtcaagctcagttgaacagaaaaaagggcctacaagacagcgcaaatgtggcttttgt aagtcaaatagagacaaggaatgtggacagttactaatatctgaaaaccagaaggtggca gcgcaccataagtgcatgctcttttcatctgctttggtatcatcacactctgataatgaa agtcttggtggattttctattgaagatgtccaaaaggaaattaaaagaggcacgaagctg atgtgttctttgtgccattgtcctggagcaacaattggttgtgatgtgaaaacatgtcac aggacataccactaccactgtgcattgcatgataaagctcaaatacgagagaaaccttca caaggaatttacatggtctattgccgaaaacacaagaaaactgcacataactccgaagct gatttagaagaaagttttaatgaacatgaactggagccctcatcacctaaaagtaaaaag aaaagtcgcaaaggaaggccaagaaaaactaattttaaagggctgtcagaagataccagg tccacatcctcccatggaacagatgaaatggaaagtagttcctatagagataggtctcca cacagaagcagccctagtgacaccaggcctaaatgtggattttgccatgtaggggaggaa gaaaatgaagcacgaggaaaactgcatatatttaatgccaagaaggcagctgcccattat aagtgcatgttgttttcttctggcacagtccagctcacaacaacatcaagagcagaattt ggagactttgatattaaaactgtacttcaggagattaaacgaggaaaaagaatgaaatgt acactttgcagtcagcctggtgctactattggatgtgaaataaaagcctgtgttaagact taccattaccactgtggagtacaagacaaagctaaatacattgaaaatatgtcacgagga atttacaaactatactgtaaaaatcatagtggaaatgatgagagagatgaagaagatgag gaacgagagagtaaaagccgaggaaaagtagaaattgatcagcaacaactaactcagcag caacttaatggaaactag |
Protein Sequence |
>84295 : length: 365 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLLISENQKVAAHHKCMLFSSALVSSHSDNE SLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPS QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGLSEDTR STSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHY KCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ QLNGN |