Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

84525

Name

HOPX

Synonym

CAMEO|HOD|HOP|LAGY|NECC1|OB1|SMAP31|TOTO;HOP homeobox;HOPX;HOP homeobox

Definition

homeodomain-only protein|lung cancer-associated Y protein|not expressed in choriocarcinoma clone 1|not expressed in choriocarcinoma protein 1|odd homeobox 1 protein|odd homeobox protein 1

Position

4q12

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

potential

"HOP may work as a tumor suppressor in a subset of glioblastomas; HOP function thus appears to be critical in the adult brain in a region of continued plasticity, and its deregulation may contribute to disease".

potential

HOP is a putative tumor suppressor gene that harbors tumor inhibitory activity.
More detail of all 2 literatures about HOPX

Pathways and Diseases

Pathway

hop pathway in cardiac development;PID BioCarta;100143

External Links

Links to Entrez Gene

84525

Links to all GeneRIF Items

84525

Links to iHOP

84525

Sequence Information

Nucleotide Sequence

>84525 : length: 222
atgtcggcggagaccgcgagcggccccacagaggaccaggtggaaatcctggagtacaac
ttcaacaaggtcgacaagcacccggattccaccacgctgtgcctcatcgcggccgaggca
ggcctttccgaggaggagacccagaaatggtttaagcagcgcctggcaaagtggcggcgc
tcagaaggcctgccctcagagtgcagatccgtcacagactaa

Protein Sequence

>84525 : length: 73
MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQRLAKWRR
SEGLPSECRSVTD



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