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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8453 |
Name | CUL2 |
Synonym | -;cullin 2;CUL2;cullin 2 |
Definition | CUL-2|cullin-2 |
Position | 10p11.21 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "Hence, Hs-cul-2 may be required for VHL function and, therefore, may be a candidate human tumor-suppressor gene. ". |
| More detail of all 1 literatures about CUL2 | |
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Pathways and Diseases |
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Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha;PID Curated;200122 |
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External Links |
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Links to Entrez Gene | 8453 |
Links to all GeneRIF Items | 8453 |
Links to iHOP | 8453 |
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Sequence Information |
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Nucleotide Sequence |
>8453 : length: 2238 atgtctttgaaaccaagagtagtagattttgatgaaacatggaacaaacttttgacgaca ataaaagccgtggtcatgttggaatacgtcgaaagagcaacatggaatgaccgtttctca gatatctatgctttatgtgtggcctatcctgaaccccttggagaaagactttatacagaa actaagatttttttggaaaatcatgttcggcatttgcataagagagttttggagtcagaa gaacaagtacttgttatgtatcataggtactgggaagaatacagcaagggtgcagactat atggactgcttatataggtatctcaacacccagtttattaaaaagaataaattaacagaa gcggaccttcagtatggctatggtggtgtagatatgaatgaaccacttatggaaatagga gagctagcattggatatgtggaggaaattgatggttgaaccacttcaggccatccttatc cgaatgctgctccgagaaatcaaaaatgatcgtggtggagaagacccaaaccagaaagta atccatggggttattaactcctttgttcatgttgaacagtataagaaaaaattcccctta aagttttatcaggaaatttttgagtctccctttctgactgaaacaggagagtattacaaa caagaagcttcaaatttattacaagaatcaaactgctcacagtatatggaaaaggttcta ggtagattaaaagatgaagaaattcgatgtcgaaaatacctacatccaagttcatatact aaggtgattcatgaatgtcaacaacgaatggtagcagaccacttacagtttttacatgca gaatgtcataatataattcgacaagagaaaaaaaatgacatggcaaatatgtacgtctta ctccgtgctgtgtccactggtttacctcatatgattcaggagctgcaaaaccacatccat gatgagggccttcgagcaaccagcaaccttactcaggaaaacatgccaacactatttgtg gagtcagttttggaagtgcatggtaaatttgttcagcttatcaacactgttttgaatggt gatcagcattttatgagtgcgttggataaggcccttacgtcagttgtaaattacagagaa cctaagtctgtttgcaaagcacctgaactgcttgctaagtactgtgacaacttactgaag aagtcagcgaaagggatgacagagaatgaagtggaagacaggctcacgagcttcatcaca gtgttcaaatacattgatgacaaggacgtctttcaaaagttctacgcaagaatgctggca aaacgtttaattcatgggttatccatgtctatggactctgaagaagccatgatcaacaaa ttaaagcaagcctgtggttatgagtttaccagcaagctacatcggatgtatacagatatg agtgtcagcgctgatctcaacaataagttcaacaattttatcaaaaaccaagacacagta atagatttgggaattagttttcaaatatatgttctacaggctggtgcgtggcctcttact caggctccttcatctacgtttgcaattccccaggaattagaaaaaagtgtacagatgttt gaattattttatagccaacatttcagtggaaggaaacttacatggttacattatctgtgt acaggtgaagttaaaatgaactatttgggcaaaccatatgtagccatggttacaacatac caaatggcagttcttcttgcctttaacaacagtgaaactgtcagttataaagagcttcag gacagcactcagatgaatgaaaaggaactgacaaaaacaatcaaatcattacttgatgtg aaaatgattaaccatgattcagaaaaggaagatattgatgcagaatcttcgttttcatta aatatgaactttagcagtaaaagaacaaaatttaaaattactacatcaatgcagaaagac acaccacaagaaatggagcagactagaagtgcagttgatgaggaccggaaaatgtatctc caagctgctatagttcgtatcatgaaagcacgaaaagtgcttcggcacaatgcccttatt caagaggtgattagccagtcaagagctaggtttaatcccagtatcagcatgattaagaag tgtattgaagttctgatagacaaacaatacatagaacgcagccaggcgtcggcagatgaa tacagctacgtcgcgtga |
Protein Sequence |
>8453 : length: 745 MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTE TKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTE ADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVL GRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMANMYVL LRAVSTGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNG DQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFIT VFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDM SVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMF ELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQ DSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKD TPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKK CIEVLIDKQYIERSQASADEYSYVA |