Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

863

Name

CBFA2T3

Synonym

ETO2|MTG16|MTGR2|ZMYND4;core-binding factor, runt domain, alpha subunit 2; translocated to, 3;CBFA2T3;core-binding factor, runt domain, alpha subunit 2; translocated to, 3

Definition

MTG8-related gene 2|MTG8-related protein 2|myeloid translocation gene 8 and 16b|myeloid translocation gene on chromosome 16 protein|protein CBFA2T3|zinc finger MYND domain-containing protein 4

Position

16q24

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

potential

"ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription."

potential

"Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes."

potential

CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.
More detail of all 3 literatures about CBFA2T3

Pathways and Diseases

Pathway

ErbB4 signaling events;PID Curated;200009

Disease

Leukemia;FunDO

Disease

Breast cancer;FunDO

External Links

Links to Entrez Gene

863

Links to all GeneRIF Items

863

Links to iHOP

863

Sequence Information

Nucleotide Sequence

>863 : length: 1962
atgccggcttcaagactgagggacagggcagccagttcagcctcgggatccacctgtggc
tccatgtcccagacgcaccctgtgctggagagcggcctcctggcatctgccggctgctcc
gcaccccggggtcccaggaagggcggcccagccccagtggacaggaaagctaaggcctca
gcgatgccggactccccagcggaggtgaagacgcagccccggtccacaccccccagcatg
ccgcccccaccgcctgccgcatcccagggggccacacgccccccctccttcacgccacac
acacatcgagaggacgggcctgcgacgctgccccacggccgttttcatggctgcttaaaa
tggtctatggtctgtctcttgatgaacggcagcagccactcaccaacagccatcaatggt
gcaccgtgcacacccaacggcttcagcaatggcccggccacctcgtccacagcctccttg
tccacacagcacctgcccccagcctgcggggcccggcagctcagcaagctcaagcgcttc
ctcaccacactgcagcagtttggcagcgacatctccccagagattggggagcgcgtgcgc
acactggtgctgggcctggtgaactcgacattgacgatcgaggagtttcattccaagctt
caggaggccaccaacttccctctgcggccgtttgtcattcccttcctgaaggcaaacctg
cccttgctgcagcgggagctcctgcactgtgcacgcctggccaagcagacgcccgcccag
tacttggcccagcatgagcagctcctgctggacgccagcgcctcctcccccatcgactcc
tcagagctgctactggaagtcaacgagaacggcaagaggaggacgcccgacaggaccaaa
gagaacgggtcagaccgcgacccgctgcaccccgagcacctcagcaaacggccatgcacc
ctgaaccctgcccagcgctacagccccagcaacgggccaccgcagcccacaccgccgccg
cactaccgcctggaggacatagccatggcccaccacttccgagatgcctaccgccaccca
gacccccgggagctacgagagcgccatcggccgcttgtggtgcctgggtcccggcaggaa
gaagtgatcgaccacaagctcacagagcgtgagtgggcagaagagtggaagcacctcaac
aacctcctgaactgcatcatggacatggtggagaagacgcggcgctcgctcacggtgctg
cgcaggtgccaggaggccgaccgcgaggagctcaaccactgggcgcggcgctacagcgac
gccgaggacacaaagaagggccccgctcccgccgcggcccggccccgcagcagctccgcc
ggtcccgaagggcctcagctagacgtgcctcgcgagttcctgccgaggaccctcaccggc
tacgtgcctgaggacatctggaggaaggctgaagaggccgtgaatgaggtgaagcggcag
gccatgtcggagctgcagaaagccgtgtcggacgcggagcgcaaagcgcacgagctcatc
accacggagcgtgccaagatggagcgggccctggccgaggcgaagcggcaggcctccgag
gacgccctgacggtcatcaaccagcaggaggactccagcgagagctgctggaactgcggg
cggaaagccagtgagacgtgcagcggctgcaacgcggcacgctactgcgggtccttctgc
cagcatcgggactgggagaagcatcaccacgtgtgtggccagagcctgcagggccccaca
gccgtggtggccgacccggtgcctggaccgcccgaagccgcccacagcctgggcccctcc
ctgcctgtgggtgctgccagccccagcgaagccggctctgcggggccttctcgccccggc
tcccccagcccacctggcccactggacaccgtgccccgctga

Protein Sequence

>863 : length: 653
MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGPAPVDRKAKAS
AMPDSPAEVKTQPRSTPPSMPPPPPAASQGATRPPSFTPHTHREDGPATLPHGRFHGCLK
WSMVCLLMNGSSHSPTAINGAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRF
LTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANL
PLLQRELLHCARLAKQTPAQYLAQHEQLLLDASASSPIDSSELLLEVNENGKRRTPDRTK
ENGSDRDPLHPEHLSKRPCTLNPAQRYSPSNGPPQPTPPPHYRLEDIAMAHHFRDAYRHP
DPRELRERHRPLVVPGSRQEEVIDHKLTEREWAEEWKHLNNLLNCIMDMVEKTRRSLTVL
RRCQEADREELNHWARRYSDAEDTKKGPAPAAARPRSSSAGPEGPQLDVPREFLPRTLTG
YVPEDIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASE
DALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVCGQSLQGPT
AVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR



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