Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

8848

Name

TSC22D1

Synonym

Ptg-2|TGFB1I4|TSC22;TSC22 domain family, member 1;TSC22D1;TSC22 domain family, member 1

Definition

TGFB-stimulated clone 22 homolog|TGFbeta-stimulated clone 22|TSC22 domain family protein 1|cerebral protein 2|regulatory protein TSC-22|transcriptional regulator TSC-22|transforming growth factor beta-1-induced transcript 4 protein|transforming growth fac

Position

13q14

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

potential

TSC-22 is a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD.

potential

TSC-22 normally contributes to the regulation of hematopoietic stem cell function and is a putative tumor suppressor gene that is hypermethylated and silenced in T or NK LGL leukemia.

potential

The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b.
More detail of all 3 literatures about TSC22D1

External Links

Links to Entrez Gene

8848

Links to all GeneRIF Items

8848

Links to iHOP

8848

Sequence Information

Nucleotide Sequence

>8848 : length: 435
atgaaatcccaatggtgtagaccagtggcgatggatctaggagtttaccaactgagacat
ttttcaatttctttcttgtcatccttgctggggactgaaaacgcttctgtgagacttgat
aatagctcctctggtgcaagtgtggtagctattgacaacaaaatcgagcaagctatggat
ctagtgaaaagccatttgatgtatgcggtcagagaagaagtggaggtcctcaaagagcaa
atcaaagaactaatagagaaaaattcccagctggagcaggagaacaatctgctgaagaca
ctggccagtcctgagcagcttgcccagtttcaggcccagctgcagactggctccccccct
gccaccacccagccacagggcaccacacagccccccgcccagccagcatcgcagggctca
ggaccaaccgcatag

Protein Sequence

>8848 : length: 144
MKSQWCRPVAMDLGVYQLRHFSISFLSSLLGTENASVRLDNSSSGASVVAIDNKIEQAMD
LVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPP
ATTQPQGTTQPPAQPASQGSGPTA



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