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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8915 |
Name | BCL10 |
Synonym | CARMEN|CIPER|CLAP|c-E10|mE10;B-cell CLL/lymphoma 10;BCL10;B-cell CLL/lymphoma 10 |
Definition | B-cell lymphoma/leukemia 10|CARD containing molecule enhancing NF-kB|CARD-containing apoptotic signaling protein|CARD-containing molecule enhancing NF-kappa-B|CARD-containing proapoptotic protein|CED-3/ICH-1 prodomain homologous E10-like regulator|cCARMEN |
Position | 1p22 |
Gene Type | protein-coding |
Source | Count: 3; TAG,Generif,UniProt |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | These data suggest that wild-type BCL10 may act as a tumor suppressor. |
| More detail of all 1 literatures about BCL10 | |
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Pathways and Diseases |
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Pathway | BCR signaling pathway;PID Curated;200005 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | TCR signaling in naive CD4+ T cells;PID Curated;200022 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | Downstream TCR signaling;PID Reactome;500482 |
Pathway | TCR signaling in naive CD8+ T cells;PID Curated;200062 |
Pathway | Canonical NF-kappaB pathway;PID Curated;200026 |
Disease | Germ cell tumor;OMIM |
Disease | blast crisis of chronic myeloid leukaemia;GAD |
Disease | Lymphoma, follicular;OMIM |
Disease | Colon cancer;OMIM |
Disease | Mesothelioma;OMIM |
Disease | Sezary syndrome;OMIM |
Disease | CANCER;GAD |
Disease | Lymphoma, MALT;OMIM |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 8915 |
Links to all GeneRIF Items | 8915 |
Links to iHOP | 8915 |
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Sequence Information |
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Nucleotide Sequence |
>8915 : length: 702 atggagcccaccgcaccgtccctcaccgaggaggacctcactgaagtgaagaaggacgcc ttagaaaatttacgtgtatacctgtgtgagaaaatcatagctgagagacattttgatcat ctacgtgcaaaaaaaatactcagtagagaagacactgaagaaatttcttgtcgaacatca agtagaaaaagggctggaaaattgttagactacttacaggaaaacccaaaaggtctggac acccttgttgaatctattcggcgagaaaaaacacagaacttcctgatacagaagattaca gatgaagtgctgaaacttagaaatataaaactagaacatctgaaaggactaaaatgtagc agttgtgaaccttttccagatggagccacgaacaacctctccagatcaaattcagatgag agtaatttctctgaaaaactgagggcatccactgtcatgtaccatccagaaggagaatcc agcacgacgccctttttttctactaattcttctctgaatttgcctgttctagaagtaggc agaactgaaaataccatcttctcttcaactacacttcccagacctggggacccaggggct cctcctttgccaccagatctacagttagaagaagaaggaacttgtgcaaactctagtgag atgtttcttcccttaagatcacgtactgtttcacgacaatga |
Protein Sequence |
>8915 : length: 233 MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTS SRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCS SCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVG RTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ |