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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8994 |
Name | LIMD1 |
Synonym | -;LIM domains containing 1;LIMD1;LIM domains containing 1 |
Definition | LIM domain-containing protein 1 |
Position | 3p21.3 |
Gene Type | protein-coding |
Source | Count: 4; Pubmed_search,TAG,Generif,UniProt |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development." |
reviewed | study demonstrates that LIMD1 represents a novel prognostic marker for breast cancer. Combined with the fact that LIMD1 expression is downregulated in lung cancers this clearly indicates that LIMD1 may represent a critical tumor suppressor gene. |
reviewed | "LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription." |
| More detail of all 3 literatures about LIMD1 | |
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External Links |
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Links to Entrez Gene | 8994 |
Links to all GeneRIF Items | 8994 |
Links to iHOP | 8994 |
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Sequence Information |
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Nucleotide Sequence |
>8994 : length: 2031 atggataagtatgacgacctgggcctggaggccagtaaattcatcgaggacctgaacatg tatgaggcctctaaggatgggctcttccgagtggacaagggtgcaggcaacaaccccgag tttgaggaaactcgcagggtgttcgccaccaagatggccaaaatccacctccagcagcag cagcagcagctcctgcaggaggagactctgcccagggggagtagaggccctgtcaatgga gggggccgcctgggcccacaggcccgttgggaagttgtgggcagcaagctgactgtggat ggtgctgccaagcctcctcttgctgcctcgacaggggcacctggggcagtcaccaccctc gctgctgggcagcccccgtacccaccgcaggagcagagatccaggccatacctgcatggc acgaggcatggcagccaggactgtggttccagggagagcctggcgacttctgagatgtct gctttccaccagccaggcccctgtgaggatccttcctgcctcactcatggagactattat gacaacctctccttggcaagcccaaagtggggtgacaaaccaggagtgtcccccagcatc ggcctgagtgtagggagtgggtggcctagctccccggggagtgacccaccactgcccaaa ccctgcggggaccatcccctaaatcaccgacagctctccctgagctccagcaggtcttct gagggtagcctcggtggtcagaatagtggcattggtggccgcagcagcgagaagccaaca ggcctttggtccactgcctcctcccagcgggtgagccctggcctgccttccccaaacttg gagaacggagcaccagctgtggggcctgttcagcccaggaccccttctgtgtcagcaccc ttggccctgagctgccccaggcaaggaggtcttccaagatcaaactcggggctggggggt gaggtttcaggtgtgatgtccaaacccaatgtggacccccaaccctggttccaggatggg cccaaatcttacctttccagttctgccccgtcatcctcgccagctggtctggacggttca cagcagggtgcggtccctgggctggggccgaagcctggctgcacagaccttggcactggt cccaagctcagccccaccagtcttgtccatccagtgatgtccaccctgcctgagttatct tgtaaagagggtcccctgggctggtcttctgatggtagcctgggatctgtgctcctggac agccccagctcccctagggtaaggctgccctgccagcccctcgtcccaggtcctgagctg agaccctctgctgctgagttgaaattagaagccctcacccaacgtctggagcgagagatg gatgctcacccgaaggctgattactttggagcctgtgtgaaatgcagcaaaggggtgttt ggggctggccaggcctgtcaggccatggggaacctctaccatgacacatgcttcacctgt gcagcttgcagccggaagctgagaggaaaagccttttattttgtcaacggcaaagtgttt tgtgaagaagacttcctgtactctggtttccagcagtcggctgacaggtgttttctttgt ggacatctgatcatggacatgatcctgcaagccctggggaagtcctaccaccccggctgt ttccgctgtgtcatctgtaatgagtgtttggatggggtgcccttcaccgtggactcagag aacaagatctactgtgtccgagattaccacaaggtgctggcccccaagtgtgcagcctgt gggcttcccatccttccacctgagggctcagatgagaccatccgtgtcgtgtccatggac agagactaccacgtggagtgttaccactgcgaggactgtggtctggagctcaatgatgaa gatggccaccgctgttatccgctggaggaccacctgttctgtcactcctgccacgtgaag aggctggagaagagaccctcatctacagcccttcaccagcaccacttctag |
Protein Sequence |
>8994 : length: 676 MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQ QQQLLQEETLPRGSRGPVNGGGRLGPQARWEVVGSKLTVDGAAKPPLAASTGAPGAVTTL AAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSS EGSLGGQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPAVGPVQPRTPSVSAP LALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLD SPSSPRVRLPCQPLVPGPELRPSAAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVF GAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLC GHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAAC GLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVK RLEKRPSSTALHQHHF |