Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

9148

Name

NEURL

Synonym

NEURL1|RNF67|bA416N2.1|neu|neu-1;neuralized homolog (Drosophila);NEURL;neuralized homolog (Drosophila)

Definition

RING finger protein 67|h-neuralized 1|neuralized-like protein 1A

Position

10q25.1

Gene Type

protein-coding

Source

Count: 2; TAG,Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

NEURL1 expression was downregulated in medulloblastoma compared to normal cerebellar tissue with lowest expression levels in hedgehog-activated tumors; conclude NEURL1 is candidate tumor suppressor in MB at least in part through effects on Notch pathway.
More detail of all 1 literatures about NEURL

Pathways and Diseases

Pathway

Notch signaling pathway;PID Curated;200013

Disease

Platelet aggregation;NHGRI

External Links

Links to Entrez Gene

9148

Links to all GeneRIF Items

9148

Links to iHOP

9148

Sequence Information

Nucleotide Sequence

>9148 : length: 1725
atgggtaacaacttctccagtatcccctcgctgccccgaggaaacccgagccgcgcgccg
cggggccacccccagaacctcaaagactctatcgggggccccttccccgtcacttctcac
cgatgccaccacaagcagaagcactgtccggcagtgctgcccagcggggggctcccagcc
acgccgctgctcttccacccgcacaccaagggctcccagatcctcatggacctcagccac
aaggctgtcaagaggcaggccagcttctgcaacgccatcaccttcagcaaccgcccggtc
ctcatctacgagcaagtcaggctgaagatcaccaagaagcagtgctgctggagcggggcc
ctgcggctgggcttcaccagcaaggacccgtcccgcatccaccctgactcgctgcccaag
tacgcctgccccgacctggtgtcccagagtggcttctgggccaaggcgctgcctgaggag
tttgccaatgagggcaacatcatcgcattctgggtggacaagaagggccgtgtcttccac
cgcatcaacgactcggctgttatgctgttcttcagcggggtccgcacggccgacccgctc
tgggccctggtggacgtctacggcctcacgcggggcgtccagctgcttgatagcgagctg
gtgctcccggactgtctgcggccgcgctccttcaccgccctgcggcggccgtcgctgcgg
cgcgaggcggacgacgcgcgcctctcggtgagcctatgcgacctcaacgtgccgggcgcg
gacggcgacgaggccgcgccggccgccggctgccccatcccgcagaactcactcaactcg
cagcacagccgcgcgctgccggcgcagctcgacggcgacctgcgtttccacgccctgcgc
gccggcgcgcacgtccgcatcctcgacgagcagacggtggcgcgcgtggagcacgggcgc
gacgagcgcgcgctcgtcttcaccagccggcccgtgcgcgtggccgagaccatcttcgtc
aaggtcacgcgctcgggtggcgcgcggcccggcgcgctgtcgttcggcgtcaccacgtgc
gaccccggcacgctgcggccggccgacctgcctttcagccctgaggccctggtggaccgc
aaggaattctgggccgtgtgccgcgtgcccgggcccctgcacagcggcgacatcctgggc
ctggtggtcaacgccgacggcgagctgcacctcagccacaatggcgcggccgccggcatg
cagctgtgcgtggacgcctcgcagccgctttggatgctcttcggcctgcacgggaccatc
acgcagatccgcatcctcggctccactatcctggccgagcggggtatcccatcactcccc
tgctcccctgcctccacgccaacctcgcccagtgccctgggcagccgcctgtctgacccc
ttgctcagcacgtgcagctctggccctctgggtagctctgctggtgggacagcccccaat
tcgccagtgagcctgcccgagtcgccagtgaccccaggtctgggccagtggagcgatgag
tgcaccatttgctatgaacacgcggtggacacggtcatctacacatgtggccacatgtgc
ctctgctacgcctgtggcctgcgcctcaagaaggctctgcacgcctgctgccccatctgc
cgccgccccatcaaggacatcatcaagacctaccgcagctcctag

Protein Sequence

>9148 : length: 574
MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA
TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA
LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH
RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR
READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR
AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC
DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM
QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP
LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC
LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS



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