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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 9590 |
Name | AKAP12 |
Synonym | AKAP250|SSeCKS;A kinase (PRKA) anchor protein 12;AKAP12;A kinase (PRKA) anchor protein 12 |
Definition | A-kinase anchor protein 12|A-kinase anchor protein, 250kDa|AKAP 250|Src-Suppressed C Kinase Substrate|kinase scaffold protein gravin|myasthenia gravis autoantigen gravin |
Position | 6q24-q25 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "In addition to genetic alterations, epigenetic mechanisms are responsible for the reduction of the tumor suppressor gene AKAP12 in human hepatocarcinogenesis." |
potential | "These findings implicate AKAP12 in the regulation of cytokinesis progression, and suggest a novel role for AKAP12 tumor suppressor." |
| More detail of all 2 literatures about AKAP12 | |
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External Links |
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Links to Entrez Gene | 9590 |
Links to all GeneRIF Items | 9590 |
Links to iHOP | 9590 |
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Sequence Information |
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Nucleotide Sequence |
>9590 : length: 5349 atgggcgccgggagctccaccgagcagcgcagcccggagcagccgcccgaggggagctcc acgccggctgagcccgagcccagcggcggcggcccctcggccgaggcggcgccagacacc accgcggaccccgccatcgctgcctcggaccccgccaccaagctcctacagaagaatggt cagctgtccaccatcaatggcgtagctgagcaagatgagctcagcctccaggagggtgac ctaaatggccagaaaggagccctgaacggtcaaggagccctaaacagccaggaggaagaa gaagtcattgtcacagaggttggacagagagactctgaagatgtgagcaaaagagactcc gataaagagatggctactaagtcagcggttgttcacgacatcacagatgatgggcaggag gagacacccgaaataatcgaacagattccttcttcagaaagcaatttagaagagctaaca caacccactgagtcccaggctaatgatattggatttaagaaggtgtttaagtttgttggc tttaaattcactgtgaaaaaggataagacagagaagcctgacactgtccagctactcact gtgaagaaagatgaaggggagggagcagcaggggctggcgaccacaaggaccccagcctt ggggctggagaagcagcatccaaagaaagcgaacccaaacaatctacagagaaacccgaa gagaccctgaagcgtgagcaaagccacgcagaaatttctcccccagccgaatctggccaa gcagtggaggaatgcaaagaggaaggagaagagaaacaagaaaaagaacctagcaagtct gcagaatctccgactagtcccgtgaccagtgaaacaggatcaaccttcaaaaaattcttc actcaaggttgggccggctggcgcaaaaagaccagtttcaggaagccgaaggaggatgaa gtggaagcttcagagaagaaaaaggaacaagagccagaaaaagtagacacagaagaagac ggaaaggcagaggttgcctccgagaaactgaccgcctccgagcaagcccacccacaggag ccggcagaaagtgcccacgagccccggttatcagctgaatatgagaaagttgagctgccc tcagaggagcaagtcagtggctcgcagggaccttctgaagagaaacctgctccgttggcg acagaagtgtttgatgagaaaatagaagtccaccaagaagaggttgtggccgaagtccac gtcagcaccgtggaggagagaaccgaagagcagaaaacggaggtggaagaaacagcaggg tctgtgccagctgaagaattggttgaaatggatgcagaacctcaggaagctgaacctgcc aaggagctggtgaagctcaaagaaacgtgtgtttccggagaggaccctacacagggagct gacctcagtcctgatgagaaggtgctgtccaaaccccccgaaggcgttgtgagtgaggtg gaaatgctgtcatcacaggagagaatgaaggtgcagggaagtccactaaagaagcttttt accagcactggcttaaaaaagctttctggaaagaaacagaaagggaaaagaggaggagga gacgaggaatcaggggagcacactcaggttccagccgattctccggacagccaggaggag caaaagggcgagagctctgcctcatcccctgaggagcccgaggagatcacgtgtctggaa aagggcttagccgaggtgcagcaggatggggaagctgaagaaggagctacttccgatgga gagaaaaaaagagaaggtgtcactccctgggcatcattcaaaaagatggtgacgcccaag aagcgtgttagacggccttcggaaagtgataaagaagatgagctggacaaggtcaagagc gctaccttgtcttccaccgagagcacagcctctgaaatgcaagaagaaatgaaagggagc gtggaagagccaaagccggaagaaccaaagcgcaaggtggatacctcagtatcttgggaa gctttaatttgtgtgggatcatccaagaaaagagcaaggagagggtcctcttctgatgag gaagggggaccaaaagcaatgggaggagaccaccagaaagctgatgaggccggaaaagac aaagagacggggacagacgggatccttgctggttcccaagaacatgatccagggcaggga agttcctccccggagcaagctggaagccctaccgaaggggagggcgtttccacctgggag tcatttaaaaggttagtcacgccaagaaaaaaatcaaagtccaagctggaagagaaaagc gaagactccatagctgggtctggtgtagaacattccactccagacactgaacccggtaaa gaagaatcctgggtctcaatcaagaagtttattcctggacgaaggaagaaaaggccagat gggaaacaagaacaagcccctgttgaagacgcagggccaacaggggccaacgaagatgac tctgatgtcccggccgtggtccctctgtctgagtatgatgctgtagaaagggagaaaatg gaggcacagcaagcccaaaaaagcgcagagcagcccgagcagaaggcagccactgaggtg tccaaggagctcagcgagagtcaggttcatatgatggcagcagctgtcgctgacgggacg agggcagctaccattattgaagaaaggtctccttcttggatatctgcttcagtgacagaa cctcttgaacaagtagaagctgaagccgcactgttaactgaggaggtattggaaagagaa gtaattgcagaagaagaaccccccacggttactgaacctctgccagagaacagagaggcc cggggcgacacggtcgttagtgaggcggaattgacccccgaagctgtgacagctgcagaa actgcagggccattgggtgccgaagaaggaaccgaagcatctgctgctgaagagaccaca gaaatggtgtcagcagtctcccagttaaccgactccccagacaccacagaggaggccact ccggtgcaggaggtggaaggtggcgtacctgacatagaagagcaagagaggcggactcaa gaggtcctccaggcagtggcagaaaaagtgaaagaggaatcccagctgcctggcaccggt gggccagaagatgtgcttcagcctgtgcagagagcagaggcagaaagaccagaagagcag gctgaagcgtcgggtctgaagaaagagacggatgtagtgttgaaagtagatgctcaggag gcaaaaactgagccttttacacaagggaaggtggtggggcagaccaccccagaaagcttt gaaaaagctcctcaagtcacagagagcatagagtccagtgagcttgtaaccacttgtcaa gccgaaaccttagctggggtaaaatcacaggagatggtgatggaacaggctatcccccct gactcggtggaaacccctacagacagtgagactgatggaagcacccccgtagccgacttt gacgcaccaggcacaacccagaaagacgagattgtggaaatccatgaggagaatgaggtc gcatctggtacccagtcagggggcacagaagcagaggcagttcctgcacagaaagagagg cctccagcaccttccagttttgtgttccaggaagaaactaaagaacaatcaaagatggaa gacactctagagcatacagataaagaggtgtcagtggaaactgtatccattctgtcaaag actgaggggactcaagaggctgaccagtatgctgatgagaaaaccaaagacgtaccattt ttcgaaggacttgaggggtctatagacacaggcataacagtcagtcgggaaaaggtcact gaagttgcccttaaaggtgaagggacagaagaagctgaatgtaaaaaggatgatgctctt gaactgcagagtcacgctaagtctcctccatcccccgtggagagagagatggtagttcaa gtcgaaagggagaaaacagaagcagagccaacccatgtgaatgaagagaagcttgagcac gaaacagctgttaccgtatctgaagaggtcagtaagcagctcctccagacagtgaatgtg cccatcatagatggggcaaaggaagtcagcagtttggaaggaagccctcctccctgccta ggtcaagaggaggcagtatgcaccaaaattcaagttcagagctctgaggcatcattcact ctaacagcggctgcagaggaggaaaaggtcttaggagaaactgccaacattttagaaaca ggtgaaacgttggagcctgcaggtgcacatttagttctggaagagaaatcctctgaaaaa aatgaagactttgccgctcatccaggggaagatgctgtgcccacagggcccgactgtcag gcaaaatcgacaccagtgatagtatctgctactaccaagaaaggcttaagttccgacctg gaaggagagaaaaccacatcactgaagtggaagtcagatgaagtcgatgagcaggttgct tgccaggaggtcaaagtgagtgtagcaattgaggatttagagcctgaaaatgggattttg gaacttgagaccaaaagcagtaaacttgtccaaaacatcatccagacagccgttgaccag tttgtacgtacagaagaaacagccaccgaaatgttgacgtctgagttacagacacaagct cacgtgataaaagctgacagccaggacgctggacaggaaacggagaaagaaggagaggaa cctcaggcctctgcacaggatgaaacaccaattacttcagccaaagaggagtcagagtca accgcagtgggacaagcacattctgatatttccaaagacatgagtgaagcctcagaaaag accatgactgttgaggtagaaggttccactgtaaatgatcagcagctggaagaggtcgtc ctcccatctgaggaagagggaggtggagctggaacaaagtctgtgccagaagatgatggt catgccttgttagcagaaagaatagagaagtcactagttgaaccgaaagaagatgaaaaa ggtgatgatgttgatgaccctgaaaaccagaactcagccctggctgatactgatgcctca ggaggcttaaccaaagagtccccagatacaaatggaccaaaacaaaaagagaaggaggat gcccaggaagtagaattgcaggaaggaaaagtgcacagtgaatcagataaagcgatcaca ccccaagcacaggaggagttacagaaacaagagagagaatctgcaaagtcagaacttaca gaatcttaa |
Protein Sequence |
>9590 : length: 1782 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDS DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPE ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE PAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVH VSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGA DLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDG EKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGS VEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD KETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKS EDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDD SDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGT RAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREA RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEAT PVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQ AEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQ AETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEV ASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDAL ELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNV PIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILET GETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDL EGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQ FVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESES TAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDG HALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKED AQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES |