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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 9988 |
Name | DMTF1 |
Synonym | DMP1|DMTF|hDMP1;cyclin D binding myb-like transcription factor 1;DMTF1;cyclin D binding myb-like transcription factor 1 |
Definition | cyclin D-binding Myb-like protein|cyclin-D-binding Myb-like transcription factor 1|cyclin-D-interacting Myb-like protein 1|hDMTF1 |
Position | 7q21 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,Generif,UniProt |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias. |
reviewed | "Loss of heterozygosity (LOH) of the hDMP1 gene was detectable in approximately 35% of human lung carcinomas, which was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53. DMP1 is a pivotal tumor suppressor for human lung cancers." |
| More detail of all 2 literatures about DMTF1 | |
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Pathways and Diseases |
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Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Disease | Bipolar disorder and major depressive disorder (combined);NHGRI |
Disease | Lung cancer;FunDO |
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External Links |
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Links to Entrez Gene | 9988 |
Links to all GeneRIF Items | 9988 |
Links to iHOP | 9988 |
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Sequence Information |
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Nucleotide Sequence |
>9988 : length: 2019 atgactgcaaccacagaagtagcagatgatgaggttactgaggggactgtgacacagata cagattttgcagaatgagcaactagatgaaatatctcccttgggtaacgaggaagtttca gcagttagccaagcatggtttacaactaaagaagataaggattctctgactaataaagga cataaatggaagcaggggatgtggtccaaggaagaaattgatattttgatgaacaatatt gaacgctatcttaaggcacgcggaataaaagatgctacagaaatcatctttgagatgtca aaagacgaaagaaaagatttctacaggactatagcatggggtctgaaccggcctttgttt gcagtttatagaagagtgcttcgcatgtatgatgacagaaaccatgtgggaaaatataca cctgaagaaattgagaagctcaaggagctccggataaagcatggcaatgactgggcaaca ataggggcggcgctaggaagaagtgcatcttctgtcaaagatcggtgccgactgatgaag gatacttgcaacacagggaagtggacagaagaagaagaaaagagacttgcagaagtggtt catgagttgacaagcactgagccaggtgacatagtcacacagggtgtgtcttgggcagct gtggctgaacgagtcggtacccgctcagaaaagcaatgtcgttctaaatggctcaactac ctgaattggaaacagagtgggggtactgaatggaccaaggaagatgaaatcaatctcatc ctcaggatagcagaacttgatgtagctgatgaaaatgacattaactgggatctgttagct gagggatggagtagtgtccgttcaccacaatggctacgaagtaaatggtggaccatcaaa aggcaaattgcaaaccataaggatgtttcgttccctgtcttaataaaaggtcttaaacag ttacatgagaaccaaaaaaacaacccaacgcttttggagaataaatcaggatctggagtt ccaaacagtaataccaattccagtgtgcagcatgttcagataagagttgcccgcttggaa gataatacagccatctcttctagccccatggcagcattgcagattccagtccagatcacc catgtttcttcagcagactctcctgctaccgttgactcagaaacaataacactaaacagt ggaacactacagacatttgagattcttccctctttccatctacagcccactggcactcca ggcacctacctacttcaaacaagctcaagccaaggccttcccctaactctgactgctagt cccacagtaaccctgacagctgctgctcctgcttctcctgaacagattattgttcatgct ttatccccagaacatttgttgaacacaagtgataatgttacagtgcagtgtcacacacca agagtcatcattcagactgttgccacagaggacatcacttcttccatatcccaagcagaa ctgacagtcgatagtgatattcagtcatctgattttcctgagcctccagacgccctagaa gcagacactttcccagatgaaattcatcaccctaagatgactgtggagccatcatttaat gatgctcatgtatccaaattcagtgaccaaaatagcacagaactgatgaatagtgttatg gtcagaacagaagaagaaatctctgacaccgaccttaaacaagaggaatcaccctctgat ttagccagtgcttatgttactgagggtttagagtctcccactatagaagaacaagttgat caaacaattgatgatgaaacaatacttatcgttccttcaccacatggctttatccaggca tctgatgttatagatactgaatctgtcttgcctttgacaacactaacagatcccatactc caacatcatcaggaagaatcaaatatcattggatcatccttgggcagtcctgtttcagaa gattcaaaggatgtcgaagatttggtaaactgtcattag |
Protein Sequence |
>9988 : length: 672 MTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKG HKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLF AVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMK DTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNY LNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIK RQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLE DNTAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSFHLQPTGTP GTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTP RVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFN DAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVD QTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSE DSKDVEDLVNCH |