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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5727 |
Name | PTCH1 |
Synonymous | BCNS|HPE7|NBCCS|PTC|PTC1|PTCH|PTCH11;patched 1;PTCH1;patched 1 |
Definition | PTCH protein +12b|PTCH protein +4'|PTCH protein -10|PTCH protein -3,4,5|patched homolog 1|protein patched homolog 1 |
Position | 9q22.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
SMO | BIOGRID; PUBMED:9811851; |
interacts with |
CDK1 | CELL_MAP; PUBMED:11331587; |
interacts with |
Shh | CELL_MAP; PUBMED:9811851; |
interacts with |
DHH | CELL_MAP; PUBMED:9811851;PUBMED:8906787; |
interacts with |
CCNB1 | CELL_MAP; PUBMED:11331587; |
interacts with |
IHH | CELL_MAP; PUBMED:9811851; |
interacts with |
SMO | CELL_MAP; PUBMED:9811851; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
metabolic catalysis |
GLI1 | NCI_NATURE; PUBMED:15087129;PUBMED:16885213; |
metabolic catalysis |
GLI1 | NCI_NATURE; PUBMED:16254602; |
metabolic catalysis |
PTCH1 | NCI_NATURE; PUBMED:16284117; |
metabolic catalysis |
IHH | NCI_NATURE; PUBMED:16284117; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
GPC3 | NCI_NATURE; PUBMED:18477453; |
reacts with |
DHH | NCI_NATURE; PUBMED:9811851; |
reacts with |
PTCH1 | NCI_NATURE; PUBMED:12123571; |
reacts with |
PTCH1 | NCI_NATURE; PUBMED:18477453; |
reacts with |
PTCH1 | NCI_NATURE; PUBMED:9811851; |
reacts with |
PTCH1 | NCI_NATURE; PUBMED:9811851;PUBMED:11027307;PUBMED:8906794; |
reacts with |
IHH | NCI_NATURE; PUBMED:9811851; |
reacts with |
SHH | NCI_NATURE; PUBMED:12123571; |
reacts with |
SHH | NCI_NATURE; PUBMED:18477453; |
reacts with |
SHH | NCI_NATURE; PUBMED:9811851;PUBMED:11027307;PUBMED:8906794; |