Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

672

Name

BRCA1

Synonymous

BRCAI|BRCC1|BROVCA1|IRIS|PNCA4|PPP1R53|PSCP|RNF53;breast cancer 1, early onset;BRCA1;breast cancer 1, early onset

Definition

BRCA1/BRCA2-containing complex, subunit 1|RING finger protein 53|breast and ovarian cancer susceptibility protein 1|breast and ovarian cancer sususceptibility protein 1|breast cancer type 1 susceptibility protein|protein phosphatase 1, regulatory subunit

Position

17q21

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

   | Top |

Interaction Type

Interactor

Data Source

interacts with

 MED21BIOGRID; PUBMED:9159119;

interacts with

 MSH3BIOGRID; PUBMED:11498787;

interacts with

 MSH3BIOGRID; PUBMED:14578343;

interacts with

 MDC1BIOGRID; PUBMED:17525332;

interacts with

 MED13BIOGRID; PUBMED:15208681;

interacts with

 MLH1BIOGRID; PUBMED:10783165;

interacts with

 MLH1BIOGRID; PUBMED:17148452;

interacts with

 MLH1BIOGRID; PUBMED:21240188;

interacts with

 MRE11ABIOGRID; PUBMED:10426999;

interacts with

 MRE11ABIOGRID; PUBMED:10783165;

interacts with

 MRE11ABIOGRID; PUBMED:11353843;

interacts with

 MRE11ABIOGRID; PUBMED:11504724;

interacts with

 MED24BIOGRID; PUBMED:15208681;

interacts with

 MSH6BIOGRID; PUBMED:10783165;

interacts with

 MSH6BIOGRID; PUBMED:11498787;

interacts with

 MSH6BIOGRID; PUBMED:16260778;

interacts with

 MED1BIOGRID; PUBMED:15208681;

interacts with

 MED17BIOGRID; PUBMED:11504724;

interacts with

 MED17BIOGRID; PUBMED:12154023;

interacts with

 MED17BIOGRID; PUBMED:15208681;

interacts with

 MED23BIOGRID; PUBMED:15208681;

interacts with

 MSH2BIOGRID; PUBMED:10783165;

interacts with

 MSH2BIOGRID; PUBMED:11498787;

interacts with

 MSH2BIOGRID; PUBMED:15886699;

interacts with

 MSH2BIOGRID; PUBMED:16260778;

interacts with

 MAP4K4BIOGRID; PUBMED:14578343;

interacts with

 MORF4L1BIOGRID; PUBMED:20332121;

interacts with

 MAP3K3BIOGRID; PUBMED:15205325;

interacts with

 TERF2BIOGRID; PUBMED:19797051;

interacts with

 TP53BP1BIOGRID; PUBMED:12364621;

interacts with

 TP53BP1BIOGRID; PUBMED:17525332;

interacts with

 TERF1BIOGRID; PUBMED:19797051;

interacts with

 VCPBIOGRID; PUBMED:10855792;

interacts with

 GTF2H4BIOGRID; PUBMED:9159119;

interacts with

 TUBG1BIOGRID; PUBMED:11691781;

interacts with

 TUBG1BIOGRID; PUBMED:15367667;

interacts with

 TUBG1BIOGRID; PUBMED:9789027;

interacts with

 RELABIOGRID; PUBMED:12700228;

interacts with

 TOP2ABIOGRID; PUBMED:15965487;

interacts with

 NCOA3BIOGRID; PUBMED:14578343;

interacts with

 NCOA3BIOGRID; PUBMED:16860316;

interacts with

 COBRA1BIOGRID; PUBMED:11739404;

interacts with

 NMIBIOGRID; PUBMED:11916966;

interacts with

 NBNBIOGRID; PUBMED:10426999;

interacts with

 NBNBIOGRID; PUBMED:10783165;

interacts with

 NBNBIOGRID; PUBMED:11504724;

interacts with

 NUP153BIOGRID; PUBMED:14578343;

interacts with

 CDK1BIOGRID; PUBMED:9244350;

interacts with

 NUFIP1BIOGRID; PUBMED:15107825;

interacts with

 NCOA2BIOGRID; PUBMED:11085509;

interacts with

 NCOA2BIOGRID; PUBMED:14578343;

interacts with

 NCOA2BIOGRID; PUBMED:16860316;

interacts with

 MYCBIOGRID; PUBMED:11916966;

interacts with

 MYCBIOGRID; PUBMED:12646176;

interacts with

 MYCBIOGRID; PUBMED:14612409;

interacts with

 MYCBIOGRID; PUBMED:20215511;

interacts with

 MYCBIOGRID; PUBMED:9788437;

interacts with

 NFYABIOGRID; PUBMED:11777930;

interacts with

 KIF1BBIOGRID; PUBMED:14578343;

interacts with

 CDK16BIOGRID; PUBMED:9738006;

interacts with

 CREBBPBIOGRID; PUBMED:10655477;

interacts with

 CREBBPBIOGRID; PUBMED:11782371;

interacts with

 CREBBPBIOGRID; PUBMED:12700228;

interacts with

 CREBBPBIOGRID; PUBMED:16860316;

interacts with

 CREBBPBIOGRID; PUBMED:9443979;

interacts with

 CREBBPBIOGRID; PUBMED:9926942;

interacts with

 CDK2BIOGRID; PUBMED:10373534;

interacts with

 CDK2BIOGRID; PUBMED:8764100;

interacts with

 CDK2BIOGRID; PUBMED:9244350;

interacts with

 CDK8BIOGRID; PUBMED:9159119;

interacts with

 ARNTBIOGRID; PUBMED:16567799;

interacts with

 BRD7BIOGRID; PUBMED:20215511;

interacts with

 ATMBIOGRID; PUBMED:10550055;

interacts with

 ATMBIOGRID; PUBMED:10608806;

interacts with

 ATMBIOGRID; PUBMED:10783165;

interacts with

 ATMBIOGRID; PUBMED:10866324;

interacts with

 ATMBIOGRID; PUBMED:11016625;

interacts with

 ATMBIOGRID; PUBMED:11114888;

interacts with

 ATMBIOGRID; PUBMED:11278964;

interacts with

 ATMBIOGRID; PUBMED:17478428;

interacts with

 ATMBIOGRID; PUBMED:18344987;

interacts with

 BARD1BIOGRID; PUBMED:10026184;

interacts with

 BARD1BIOGRID; PUBMED:10477523;

interacts with

 BARD1BIOGRID; PUBMED:10635334;

interacts with

 BARD1BIOGRID; PUBMED:11257228;

interacts with

 BARD1BIOGRID; PUBMED:11278247;

interacts with

 BARD1BIOGRID; PUBMED:11301010;

interacts with

 BARD1BIOGRID; PUBMED:11498787;

interacts with

 BARD1BIOGRID; PUBMED:11504724;

interacts with

 BARD1BIOGRID; PUBMED:11526114;

interacts with

 BARD1BIOGRID; PUBMED:11573085;

interacts with

 BARD1BIOGRID; PUBMED:11773071;

interacts with

 BARD1BIOGRID; PUBMED:11925436;

interacts with

 BARD1BIOGRID; PUBMED:11927591;

interacts with

 BARD1BIOGRID; PUBMED:12431996;

interacts with

 BARD1BIOGRID; PUBMED:12438698;

interacts with

 BARD1BIOGRID; PUBMED:12485996;

interacts with

 BARD1BIOGRID; PUBMED:12700228;

interacts with

 BARD1BIOGRID; PUBMED:12732733;

interacts with

 BARD1BIOGRID; PUBMED:12890688;

interacts with

 BARD1BIOGRID; PUBMED:12951069;

interacts with

 BARD1BIOGRID; PUBMED:14636569;

interacts with

 BARD1BIOGRID; PUBMED:14638690;

interacts with

 BARD1BIOGRID; PUBMED:14647430;

interacts with

 BARD1BIOGRID; PUBMED:15159397;

interacts with

 BARD1BIOGRID; PUBMED:16489000;

interacts with

 BARD1BIOGRID; PUBMED:17525341;

interacts with

 BARD1BIOGRID; PUBMED:17664283;

interacts with

 BARD1BIOGRID; PUBMED:18936166;

interacts with

 BARD1BIOGRID; PUBMED:19117993;

interacts with

 BARD1BIOGRID; PUBMED:19176389;

interacts with

 BARD1BIOGRID; PUBMED:20215511;

interacts with

 BARD1BIOGRID; PUBMED:8944023;

interacts with

 BARD1BIOGRID; PUBMED:9342365;

interacts with

 BARD1BIOGRID; PUBMED:9738006;

interacts with

 BARD1BIOGRID; PUBMED:9788437;

interacts with

 BRCA2BIOGRID; PUBMED:11477095;

interacts with

 BRCA2BIOGRID; PUBMED:14499622;

interacts with

 BRCA2BIOGRID; PUBMED:14636569;

interacts with

 BRCA2BIOGRID; PUBMED:17664283;

interacts with

 BRCA2BIOGRID; PUBMED:21135251;

interacts with

 BRCA2BIOGRID; PUBMED:9774970;

interacts with

 BLMBIOGRID; PUBMED:10783165;

interacts with

 ATF1BIOGRID; PUBMED:10945975;

interacts with

 BRCC3BIOGRID; PUBMED:14636569;

interacts with

 BRCC3BIOGRID; PUBMED:17664283;

interacts with

 BREBIOGRID; PUBMED:14636569;

interacts with

 BACH1BIOGRID; PUBMED:11301010;

interacts with

 BACH1BIOGRID; PUBMED:15125843;

interacts with

 BACH1BIOGRID; PUBMED:17664283;

interacts with

 ATRBIOGRID; PUBMED:10608806;

interacts with

 ATRBIOGRID; PUBMED:11016625;

interacts with

 ATRBIOGRID; PUBMED:11114888;

interacts with

 ATRBIOGRID; PUBMED:11278964;

interacts with

 ATRBIOGRID; PUBMED:17478428;

interacts with

 BRAPBIOGRID; PUBMED:8955125;

interacts with

 BRAPBIOGRID; PUBMED:9497340;

interacts with

 AURKABIOGRID; PUBMED:14990569;

interacts with

 ESR1BIOGRID; PUBMED:11244506;

interacts with

 ESR1BIOGRID; PUBMED:11493692;

interacts with

 ESR1BIOGRID; PUBMED:11782371;

interacts with

 ESR1BIOGRID; PUBMED:12400015;

interacts with

 ESR1BIOGRID; PUBMED:16061635;

interacts with

 ESR1BIOGRID; PUBMED:16260778;

interacts with

 ESR1BIOGRID; PUBMED:16860316;

interacts with

 E2F4BIOGRID; PUBMED:9244350;

interacts with

 ETS1BIOGRID; PUBMED:11313879;

interacts with

 ELK4BIOGRID; PUBMED:11313879;

interacts with

 H2AFYBIOGRID; PUBMED:12419249;

interacts with

 HIST2H2ACBIOGRID; PUBMED:11927591;

interacts with

 H2AFXBIOGRID; PUBMED:10959836;

interacts with

 H2AFXBIOGRID; PUBMED:11927591;

interacts with

 H2AFXBIOGRID; PUBMED:12485996;

interacts with

 H2AFXBIOGRID; PUBMED:18344987;

interacts with

 H2AFXBIOGRID; PUBMED:19805520;

interacts with

 HSPA8BIOGRID; PUBMED:9738006;

interacts with

 HDAC2BIOGRID; PUBMED:10220405;

interacts with

 HIST2H3ABIOGRID; PUBMED:12419249;

interacts with

 HDAC1BIOGRID; PUBMED:10220405;

interacts with

 FLI1BIOGRID; PUBMED:11313879;

interacts with

 FHL2BIOGRID; PUBMED:14550570;

interacts with

 FHL2BIOGRID; PUBMED:14986435;

interacts with

 FANCD2BIOGRID; PUBMED:11239454;

interacts with

 FANCD2BIOGRID; PUBMED:12887909;

interacts with

 FANCD2BIOGRID; PUBMED:14499622;

interacts with

 FOXO3BIOGRID; PUBMED:18344987;

interacts with

 BRIP1BIOGRID; PUBMED:11877378;

interacts with

 BRIP1BIOGRID; PUBMED:14576433;

interacts with

 BRIP1BIOGRID; PUBMED:14578343;

interacts with

 BRIP1BIOGRID; PUBMED:15133502;

interacts with

 BRIP1BIOGRID; PUBMED:15208681;

interacts with

 BRIP1BIOGRID; PUBMED:15242590;

interacts with

 BRIP1BIOGRID; PUBMED:17525341;

interacts with

 BRIP1BIOGRID; PUBMED:17525342;

interacts with

 BRIP1BIOGRID; PUBMED:17581638;

interacts with

 BRIP1BIOGRID; PUBMED:20173781;

interacts with

 BRIP1BIOGRID; PUBMED:21240188;

interacts with

 FANCABIOGRID; PUBMED:12354784;

interacts with

 FANCABIOGRID; PUBMED:21240188;

interacts with

 EP300BIOGRID; PUBMED:10655477;

interacts with

 EP300BIOGRID; PUBMED:11782371;

interacts with

 CCNA1BIOGRID; PUBMED:9244350;

interacts with

 CDKN2DBIOGRID; PUBMED:17334399;

interacts with

 CSTF2BIOGRID; PUBMED:10477523;

interacts with

 CSTF2BIOGRID; PUBMED:11257228;

interacts with

 CTCFLBIOGRID; PUBMED:14578343;

interacts with

 CSNK2A1BIOGRID; PUBMED:10403822;

interacts with

 DNAJA3BIOGRID; PUBMED:14578343;

interacts with

 CTBP1BIOGRID; PUBMED:10196224;

interacts with

 CSTF1BIOGRID; PUBMED:11257228;

interacts with

 DHX9BIOGRID; PUBMED:12592385;

interacts with

 DHX9BIOGRID; PUBMED:9662397;

interacts with

 CSNK2BBIOGRID; PUBMED:10403822;

interacts with

 CDK4BIOGRID; PUBMED:17334399;

interacts with

 CDK4BIOGRID; PUBMED:9244350;

interacts with

 JUNBIOGRID; PUBMED:12080089;

interacts with

 JAK2BIOGRID; PUBMED:11163768;

interacts with

 JUNBBIOGRID; PUBMED:12080089;

interacts with

 JUNDBIOGRID; PUBMED:12080089;

interacts with

 KAT2ABIOGRID; PUBMED:16260778;

interacts with

 CDK5BIOGRID; PUBMED:9244350;

interacts with

 RAD51BIOGRID; PUBMED:11498787;

interacts with

 RAD51BIOGRID; PUBMED:14636569;

interacts with

 RAD51BIOGRID; PUBMED:9008167;

interacts with

 RAD51BIOGRID; PUBMED:9774970;

interacts with

 RPA1BIOGRID; PUBMED:21240188;

interacts with

 RB1BIOGRID; PUBMED:10220405;

interacts with

 RB1BIOGRID; PUBMED:10518542;

interacts with

 RB1BIOGRID; PUBMED:11521194;

interacts with

 RBL1BIOGRID; PUBMED:11521194;

interacts with

 RBBP4BIOGRID; PUBMED:10220405;

interacts with

 POLR2ABIOGRID; PUBMED:11504724;

interacts with

 POLR2ABIOGRID; PUBMED:12955082;

interacts with

 POLR2ABIOGRID; PUBMED:14506230;

interacts with

 POLR2ABIOGRID; PUBMED:15886201;

interacts with

 POLR2ABIOGRID; PUBMED:9159119;

interacts with

 MRPL36BIOGRID; PUBMED:16462773;

interacts with

 RAD50BIOGRID; PUBMED:10426999;

interacts with

 RAD50BIOGRID; PUBMED:10783165;

interacts with

 RAD50BIOGRID; PUBMED:11504724;

interacts with

 RAD50BIOGRID; PUBMED:16260778;

interacts with

 RFC1BIOGRID; PUBMED:10783165;

interacts with

 JAK1BIOGRID; PUBMED:11163768;

interacts with

 RBBP7BIOGRID; PUBMED:10220405;

interacts with

 RBBP7BIOGRID; PUBMED:11394910;

interacts with

 RBBP7BIOGRID; PUBMED:11746496;

interacts with

 RBL2BIOGRID; PUBMED:11521194;

interacts with

 CCNA2BIOGRID; PUBMED:10373534;

interacts with

 ACACABIOGRID; PUBMED:12360400;

interacts with

 ACACABIOGRID; PUBMED:16326698;

interacts with

 APLP2BIOGRID; PUBMED:11746496;

interacts with

 ARBIOGRID; PUBMED:11016951;

interacts with

 ARBIOGRID; PUBMED:11085509;

interacts with

 ABL1BIOGRID; PUBMED:12024016;

interacts with

 PRMT1BIOGRID; PUBMED:20614009;

interacts with

 AKT1BIOGRID; PUBMED:10542266;

interacts with

 AKT1BIOGRID; PUBMED:19074868;

interacts with

 CCNB1BIOGRID; PUBMED:9244350;

interacts with

 PRKDCBIOGRID; PUBMED:10608806;

interacts with

 PIAS4BIOGRID; PUBMED:20016594;

interacts with

 PIAS4BIOGRID; PUBMED:20016603;

interacts with

 PIAS1BIOGRID; PUBMED:20016594;

interacts with

 PIAS1BIOGRID; PUBMED:20016603;

interacts with

 POU2F1BIOGRID; PUBMED:11777930;

interacts with

 POU2F1BIOGRID; PUBMED:18000219;

interacts with

 PEG3BIOGRID; PUBMED:11746496;

interacts with

 PPP1R3ABIOGRID; PUBMED:17511879;

interacts with

 PPP1CBBIOGRID; PUBMED:17511879;

interacts with

 KPNA2BIOGRID; PUBMED:8955125;

interacts with

 PPP1CABIOGRID; PUBMED:12438214;

interacts with

 PPP1CABIOGRID; PUBMED:17511879;

interacts with

 CCNE1BIOGRID; PUBMED:17525332;

interacts with

 GTF2E1BIOGRID; PUBMED:9159119;

interacts with

 STAT5ABIOGRID; PUBMED:12459499;

interacts with

 GTF2F1BIOGRID; PUBMED:9159119;

interacts with

 SMARCB1BIOGRID; PUBMED:10943845;

interacts with

 SRCBIOGRID; PUBMED:16860316;

interacts with

 SMARCA4BIOGRID; PUBMED:10943845;

interacts with

 SMARCA4BIOGRID; PUBMED:15034933;

interacts with

 SP1BIOGRID; PUBMED:12706836;

interacts with

 STAT1BIOGRID; PUBMED:10792030;

interacts with

 SMARCA2BIOGRID; PUBMED:15034933;

interacts with

 SMARCC1BIOGRID; PUBMED:10943845;

interacts with

 SMARCD2BIOGRID; PUBMED:10943845;

interacts with

 CDS1BIOGRID; PUBMED:12438214;

interacts with

 ZNF350BIOGRID; PUBMED:11090615;

interacts with

 WNT2BBIOGRID; PUBMED:11746496;

interacts with

 XRCC5BIOGRID; PUBMED:18936166;

interacts with

 ZCCHC8BIOGRID; PUBMED:17525332;

interacts with

 UBA1BIOGRID; PUBMED:11278247;

interacts with

 UBA1BIOGRID; PUBMED:11927591;

interacts with

 UBA1BIOGRID; PUBMED:12438698;

interacts with

 UBA1BIOGRID; PUBMED:12485996;

interacts with

 UBA1BIOGRID; PUBMED:14638690;

interacts with

 UIMC1BIOGRID; PUBMED:17525341;

interacts with

 UIMC1BIOGRID; PUBMED:17525342;

interacts with

 UIMC1BIOGRID; PUBMED:19615732;

interacts with

 UBE3ABIOGRID; PUBMED:12890688;

interacts with

 TRRAPBIOGRID; PUBMED:16260778;

interacts with

 UBE2IBIOGRID; PUBMED:20016594;

interacts with

 WDR48BIOGRID; PUBMED:19615732;

interacts with

 USF2BIOGRID; PUBMED:14502648;

interacts with

 UBE2D1BIOGRID; PUBMED:11278247;

interacts with

 UBE2D1BIOGRID; PUBMED:11927591;

interacts with

 UBE2D1BIOGRID; PUBMED:12438698;

interacts with

 UBE2D1BIOGRID; PUBMED:12485996;

interacts with

 UBE2D1BIOGRID; PUBMED:12732733;

interacts with

 UBE2D1BIOGRID; PUBMED:12890688;

interacts with

 UBE2D1BIOGRID; PUBMED:14636569;

interacts with

 UBE2D1BIOGRID; PUBMED:14638690;

interacts with

 UBE2J1BIOGRID; PUBMED:19690564;

interacts with

 UBE2L3BIOGRID; PUBMED:12732733;

interacts with

 CCND1BIOGRID; PUBMED:17334399;

interacts with

 CCND1BIOGRID; PUBMED:9244350;

interacts with

 Ifi204BIOGRID; PUBMED:14654789;

interacts with

 PALB2BIOGRID; PUBMED:19268590;

interacts with

 PALB2BIOGRID; PUBMED:19553677;

interacts with

 PALB2BIOGRID; PUBMED:19584259;

interacts with

 TP53BIOGRID; PUBMED:14636569;

interacts with

 TP53BIOGRID; PUBMED:14710355;

interacts with

 TP53BIOGRID; PUBMED:9482880;

interacts with

 TP53BIOGRID; PUBMED:9582019;

interacts with

 TP53BIOGRID; PUBMED:9926942;

interacts with

 ORC2BIOGRID; PUBMED:17525332;

interacts with

 ORC3BIOGRID; PUBMED:17525332;

interacts with

 CLSPNBIOGRID; PUBMED:15096610;

interacts with

 RBBP8BIOGRID; PUBMED:10196224;

interacts with

 RBBP8BIOGRID; PUBMED:10764811;

interacts with

 RBBP8BIOGRID; PUBMED:10910365;

interacts with

 RBBP8BIOGRID; PUBMED:11689934;

interacts with

 RBBP8BIOGRID; PUBMED:14578343;

interacts with

 RBBP8BIOGRID; PUBMED:16818604;

interacts with

 RBBP8BIOGRID; PUBMED:17525342;

interacts with

 RBBP8BIOGRID; PUBMED:9738006;

interacts with

 RBBP8BIOGRID; PUBMED:9811458;

interacts with

 CHEK2BIOGRID; PUBMED:10724175;

interacts with

 CHEK2BIOGRID; PUBMED:18804494;

interacts with

 ARCELL_MAP; PUBMED:11085509;

interacts with

 AKT1INTACT; PUBMED:21242970;

interacts with

 MLH1MINT; PUBMED:17581638;

interacts with

 NCK1MINT; PUBMED:17474147;

interacts with

 BARD1MINT; PUBMED:11573085;

interacts with

 BRAPMINT; PUBMED:9497340;

interacts with

 ESR1MINT; PUBMED:11244506;

interacts with

 GFI1BMINT; PUBMED:16713569;

interacts with

 FANCD2MINT; PUBMED:11239454;

interacts with

 BRIP1MINT; PUBMED:14576432;

interacts with

 BRIP1MINT; PUBMED:17581638;

interacts with

 FANCAMINT; PUBMED:12354784;

interacts with

 JAK2MINT; PUBMED:11163768;

interacts with

 RAD23BMINT; PUBMED:16712842;

interacts with

 JAK1MINT; PUBMED:11163768;

interacts with

 ABL1MINT; DOI:10.1002/pmic.200600966;

interacts with

 PMS2MINT; PUBMED:17581638;

interacts with

 PIK3R1MINT; PUBMED:17474147;

interacts with

 BARD1NCI_NATURE; PUBMED:11927591;PUBMED:11278247;

interacts with

 BRCA1NCI_NATURE; PUBMED:11927591;PUBMED:11278247;

Metabolic Interaction

   | Top |

Interaction Type

Interactor

Data Source

metabolic catalysis

 TFDP2NCI_NATURE; PUBMED:16357170;

metabolic catalysis

 E2F4NCI_NATURE; PUBMED:16357170;

metabolic catalysis

 E2F6NCI_NATURE; PUBMED:12909625;

Signaling Interaction

   | Top |

Interaction Type

Interactor

Data Source

reacts with

 MDC1NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 MDC1NCI_NATURE; PUBMED:17525340;

reacts with

 MDC1NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 MDC1NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 MRE11ANCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 MRE11ANCI_NATURE; PUBMED:16391231;

reacts with

 MRE11ANCI_NATURE; PUBMED:17525340;

reacts with

 MRE11ANCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 MRE11ANCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 TP53BP1NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 TP53BP1NCI_NATURE; PUBMED:17525340;

reacts with

 TP53BP1NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 TP53BP1NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 TOPBP1NCI_NATURE; PUBMED:16391231;

reacts with

 NBNNCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 NBNNCI_NATURE; PUBMED:16391231;

reacts with

 NBNNCI_NATURE; PUBMED:17525340;

reacts with

 NBNNCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 NBNNCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 NF1NCI_NATURE; PUBMED:17700520;

state change

 CDK2NCI_NATURE; PUBMED:15665273;

reacts with

 ATMNCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 ATMNCI_NATURE; PUBMED:17525340;

reacts with

 ATMNCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 ATMNCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

state change

 ATMNCI_NATURE; PUBMED:10910365;

state change

 ATMNCI_NATURE; PUBMED:16391231;

reacts with

 BARD1NCI_NATURE; PUBMED:10477523;PUBMED:11943588;

reacts with

 BARD1NCI_NATURE; PUBMED:10910365;

reacts with

 BARD1NCI_NATURE; PUBMED:12154023;PUBMED:15905410;PUBMED:15886201;

reacts with

 BARD1NCI_NATURE; PUBMED:12431996;PUBMED:8944023;

reacts with

 BARD1NCI_NATURE; PUBMED:12732733;

reacts with

 BARD1NCI_NATURE; PUBMED:15159397;

reacts with

 BARD1NCI_NATURE; PUBMED:15665273;

reacts with

 BARD1NCI_NATURE; PUBMED:16391231;

reacts with

 BARD1NCI_NATURE; PUBMED:9267023;

reacts with

 BARD1NCI_NATURE; PUBMED:9738006;PUBMED:9811458;PUBMED:10764811;

reacts with

 BRCA1NCI_NATURE; PUBMED:10477523;PUBMED:11943588;

reacts with

 BRCA1NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 BRCA1NCI_NATURE; PUBMED:10910365;

reacts with

 BRCA1NCI_NATURE; PUBMED:11301010;

reacts with

 BRCA1NCI_NATURE; PUBMED:12154023;PUBMED:15905410;PUBMED:15886201;

reacts with

 BRCA1NCI_NATURE; PUBMED:12431996;PUBMED:8944023;

reacts with

 BRCA1NCI_NATURE; PUBMED:12732733;

reacts with

 BRCA1NCI_NATURE; PUBMED:14990569;

reacts with

 BRCA1NCI_NATURE; PUBMED:15159397;

reacts with

 BRCA1NCI_NATURE; PUBMED:15665273;

reacts with

 BRCA1NCI_NATURE; PUBMED:15674350;PUBMED:11244506;

reacts with

 BRCA1NCI_NATURE; PUBMED:16391231;

reacts with

 BRCA1NCI_NATURE; PUBMED:17525340;

reacts with

 BRCA1NCI_NATURE; PUBMED:17700520;

reacts with

 BRCA1NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 BRCA1NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 BRCA1NCI_NATURE; PUBMED:9267023;

reacts with

 BRCA1NCI_NATURE; PUBMED:9738006;PUBMED:9811458;PUBMED:10764811;

reacts with

 ATF2NCI_NATURE; PUBMED:17700520;

state change

 ATRNCI_NATURE; PUBMED:15159397;

reacts with

 AURKANCI_NATURE; PUBMED:14990569;

reacts with

 FAM175ANCI_NATURE; PUBMED:17525340;

reacts with

 FAM175ANCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 ESR1NCI_NATURE; PUBMED:15674350;PUBMED:11244506;

reacts with

 H2AFXNCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 H2AFXNCI_NATURE; PUBMED:17525340;

reacts with

 H2AFXNCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 H2AFXNCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 CTBP1NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 CTBP1NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 CSTF1NCI_NATURE; PUBMED:10477523;PUBMED:11943588;

reacts with

 RAD51NCI_NATURE; PUBMED:9267023;

reacts with

 RNF8NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 RNF8NCI_NATURE; PUBMED:17525340;

reacts with

 RNF8NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 RNF8NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 RAD50NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 RAD50NCI_NATURE; PUBMED:16391231;

reacts with

 RAD50NCI_NATURE; PUBMED:17525340;

reacts with

 RAD50NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 RAD50NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 POU2F1NCI_NATURE; PUBMED:17700520;

state change

 CCNE1NCI_NATURE; PUBMED:15665273;

reacts with

 UIMC1NCI_NATURE; PUBMED:18006705;PUBMED:18001825;PUBMED:17525340;PUBMED:18001824;

reacts with

 UBE2D3NCI_NATURE; PUBMED:12732733;

reacts with

 TP53NCI_NATURE; PUBMED:15159397;

reacts with

 PCNANCI_NATURE; PUBMED:9267023;

reacts with

 RBBP8NCI_NATURE; PUBMED:10550055;PUBMED:18006705;PUBMED:12607005;PUBMED:10910365;PUBMED:18001825;PUBMED:11313470;PUBMED:12611903;PUBMED:18001824;

reacts with

 RBBP8NCI_NATURE; PUBMED:10910365;

reacts with

 RBBP8NCI_NATURE; PUBMED:16391231;

reacts with

 RBBP8NCI_NATURE; PUBMED:18006705;PUBMED:10910365;PUBMED:12607005;PUBMED:12183412;PUBMED:18001825;PUBMED:18001824;

reacts with

 RBBP8NCI_NATURE; PUBMED:9738006;PUBMED:9811458;PUBMED:10764811;

reacts with

 MDC1REACTOME; PUBMED:12778123;PUBMED:12364621;PUBMED:11756551;

state change

 MDC1REACTOME; PUBMED:10550055;PUBMED:12773400;PUBMED:12611903;

state change

 MDC1REACTOME; PUBMED:12778123;PUBMED:12364621;PUBMED:12611903;PUBMED:11756551;

state change

 MND1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16407260;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 TP53BP1REACTOME; PUBMED:12778123;PUBMED:12364621;PUBMED:11756551;

state change

 TEX15REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18283110;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 ATMREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 ATMREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 ATMREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 BRCA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 BRCA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 BRCA2REACTOME; PUBMED:19369211;PUBMED:17549079;PUBMED:16793542;

state change

 BRCA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 BRCA1REACTOME; PUBMED:12778123;PUBMED:12364621;PUBMED:11756551;

reacts with

 BRCA1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 BRCA1REACTOME; PUBMED:19146767;

reacts with

 BRCA1REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 BRCA1REACTOME; PUBMED:19369211;PUBMED:17549079;PUBMED:16793542;

state change

 BRCA1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 ATRREACTOME; PUBMED:19146767;

reacts with

 HIST3H3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 HIST3H3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 HIST3H3REACTOME; PUBMED:19146767;

reacts with

 HIST3H3REACTOME; PUBMED:19146767;PUBMED:9008167;

state change

 HIST3H3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 H2AFXREACTOME; PUBMED:12778123;PUBMED:12364621;PUBMED:11756551;

reacts with

 H2AFXREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 H2AFXREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 H2AFXREACTOME; PUBMED:19146767;

reacts with

 H2AFXREACTOME; PUBMED:19146767;PUBMED:9008167;

state change

 H2AFXREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 PSMC3IPREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16407260;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 DMC1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 DMC1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 DMC1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 CDK4REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 CDK4REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 CDK4REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 RAD51REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 RAD51REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 RAD51REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 RPA1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 RPA1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 RPA1REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 REC8REACTOME; PUBMED:19146767;

reacts with

 REC8REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 RAD21REACTOME; PUBMED:19146767;

reacts with

 RAD21REACTOME; PUBMED:19146767;PUBMED:9008167;

state change

 RAD51CREACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:17312021;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 RPA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 RPA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 RPA2REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 RPA3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:20062530;PUBMED:18535008;PUBMED:9311981;PUBMED:9826763;PUBMED:16123081;PUBMED:10562567;PUBMED:9008167;PUBMED:17541404;

reacts with

 RPA3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

state change

 RPA3REACTOME; PUBMED:17981954;PUBMED:15164066;PUBMED:9450758;PUBMED:18256600;PUBMED:9311981;PUBMED:16123081;PUBMED:10562567;PUBMED:10438626;PUBMED:8929543;

reacts with

 SYCP3REACTOME; PUBMED:19146767;

reacts with

 SYCP3REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 SYCP2REACTOME; PUBMED:19146767;

reacts with

 SYCP2REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 STAG3REACTOME; PUBMED:19146767;

reacts with

 STAG3REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 SMC1AREACTOME; PUBMED:19146767;

reacts with

 SMC1AREACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 SMC3REACTOME; PUBMED:19146767;

reacts with

 SMC3REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 STAG1REACTOME; PUBMED:19146767;

reacts with

 STAG1REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 STAG2REACTOME; PUBMED:19146767;

reacts with

 STAG2REACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 SMC1BREACTOME; PUBMED:19146767;

reacts with

 SMC1BREACTOME; PUBMED:19146767;PUBMED:9008167;

reacts with

 PALB2REACTOME; PUBMED:19369211;PUBMED:17549079;PUBMED:16793542;

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