Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

7428

Name

VHL

Synonymous

HRCA1|RCA1|VHL1;von Hippel-Lindau tumor suppressor;VHL;von Hippel-Lindau tumor suppressor

Definition

elongin binding protein|pVHL|protein G7|von Hippel-Lindau disease tumor suppressor

Position

3p25.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 MYL12ABIOGRID; PUBMED:17353931;

interacts with

 MOBKL3BIOGRID; PUBMED:17353931;

interacts with

 MCM7BIOGRID; PUBMED:21658608;

interacts with

 MYBBP1ABIOGRID; PUBMED:21386990;

interacts with

 CCDC59BIOGRID; PUBMED:17353931;

interacts with

 TXNBIOGRID; PUBMED:17353931;

interacts with

 CCT3BIOGRID; PUBMED:11865071;

interacts with

 TRIM28BIOGRID; PUBMED:12682018;

interacts with

 TPT1BIOGRID; PUBMED:17353931;

interacts with

 TGFB1I1BIOGRID; PUBMED:17353931;

interacts with

 TAGLN2BIOGRID; PUBMED:17353931;

interacts with

 NEDD8BIOGRID; PUBMED:17353931;

interacts with

 NR4A1BIOGRID; PUBMED:18305400;

interacts with

 CCDC82BIOGRID; PUBMED:17353931;

interacts with

 KNTC1BIOGRID; PUBMED:17353931;

interacts with

 PRKCIBIOGRID; PUBMED:11574546;

interacts with

 CDK2BIOGRID; PUBMED:17353931;

interacts with

 ATMBIOGRID; PUBMED:16678111;

interacts with

 ATXN2BIOGRID; PUBMED:17353931;

interacts with

 CAB39BIOGRID; PUBMED:17353931;

interacts with

 TCEB2BIOGRID; PUBMED:10587522;

interacts with

 TCEB2BIOGRID; PUBMED:10823831;

interacts with

 TCEB2BIOGRID; PUBMED:12004076;

interacts with

 TCEB2BIOGRID; PUBMED:12048197;

interacts with

 TCEB2BIOGRID; PUBMED:12604794;

interacts with

 TCEB2BIOGRID; PUBMED:17353931;

interacts with

 TCEB2BIOGRID; PUBMED:18173839;

interacts with

 TCEB2BIOGRID; PUBMED:19030229;

interacts with

 HIF1ABIOGRID; PUBMED:10823831;

interacts with

 HIF1ABIOGRID; PUBMED:10878807;

interacts with

 HIF1ABIOGRID; PUBMED:10944113;

interacts with

 HIF1ABIOGRID; PUBMED:10973499;

interacts with

 HIF1ABIOGRID; PUBMED:11292861;

interacts with

 HIF1ABIOGRID; PUBMED:11331613;

interacts with

 HIF1ABIOGRID; PUBMED:11504942;

interacts with

 HIF1ABIOGRID; PUBMED:11566883;

interacts with

 HIF1ABIOGRID; PUBMED:11641274;

interacts with

 HIF1ABIOGRID; PUBMED:11865071;

interacts with

 HIF1ABIOGRID; PUBMED:12004076;

interacts with

 HIF1ABIOGRID; PUBMED:12050673;

interacts with

 HIF1ABIOGRID; PUBMED:12464182;

interacts with

 HIF1ABIOGRID; PUBMED:12538644;

interacts with

 HIF1ABIOGRID; PUBMED:12606543;

interacts with

 HIF1ABIOGRID; PUBMED:12682018;

interacts with

 HIF1ABIOGRID; PUBMED:12808024;

interacts with

 HIF1ABIOGRID; PUBMED:12925778;

interacts with

 HIF1ABIOGRID; PUBMED:14556007;

interacts with

 HIF1ABIOGRID; PUBMED:14600153;

interacts with

 HIF1ABIOGRID; PUBMED:14691445;

interacts with

 HIF1ABIOGRID; PUBMED:15721254;

interacts with

 HIF1ABIOGRID; PUBMED:15805242;

interacts with

 HIF1ABIOGRID; PUBMED:16278378;

interacts with

 HIF1ABIOGRID; PUBMED:16611863;

interacts with

 HIF1ABIOGRID; PUBMED:17047048;

interacts with

 HIF1ABIOGRID; PUBMED:17132228;

interacts with

 HIF1ABIOGRID; PUBMED:17558023;

interacts with

 HIF1ABIOGRID; PUBMED:17973296;

interacts with

 HIF1ABIOGRID; PUBMED:17981124;

interacts with

 HIF1ABIOGRID; PUBMED:18264140;

interacts with

 HIF1ABIOGRID; PUBMED:18305400;

interacts with

 HIF1ABIOGRID; PUBMED:18426857;

interacts with

 HIF1ABIOGRID; PUBMED:18694926;

interacts with

 HIF1ABIOGRID; PUBMED:18985005;

interacts with

 HIST1H2BCBIOGRID; PUBMED:17353931;

interacts with

 HIF3ABIOGRID; PUBMED:12538644;

interacts with

 HDAC3BIOGRID; PUBMED:11641274;

interacts with

 HAS1BIOGRID; PUBMED:17353931;

interacts with

 RASGRP1BIOGRID; PUBMED:17353931;

interacts with

 HDAC2BIOGRID; PUBMED:11641274;

interacts with

 HDAC1BIOGRID; PUBMED:11641274;

interacts with

 EPAS1BIOGRID; PUBMED:10823831;

interacts with

 EPAS1BIOGRID; PUBMED:10878807;

interacts with

 EPAS1BIOGRID; PUBMED:11331613;

interacts with

 EPAS1BIOGRID; PUBMED:12604794;

interacts with

 EPAS1BIOGRID; PUBMED:17967880;

interacts with

 HIF1ANBIOGRID; PUBMED:11641274;

interacts with

 TCEB1BIOGRID; PUBMED:10421634;

interacts with

 TCEB1BIOGRID; PUBMED:10587522;

interacts with

 TCEB1BIOGRID; PUBMED:10823831;

interacts with

 TCEB1BIOGRID; PUBMED:11739384;

interacts with

 TCEB1BIOGRID; PUBMED:12004076;

interacts with

 TCEB1BIOGRID; PUBMED:12604794;

interacts with

 TCEB1BIOGRID; PUBMED:17353931;

interacts with

 TCEB1BIOGRID; PUBMED:17558023;

interacts with

 TCEB1BIOGRID; PUBMED:18305400;

interacts with

 TCEB1BIOGRID; PUBMED:19030229;

interacts with

 TCEB1BIOGRID; PUBMED:8674032;

interacts with

 FN1BIOGRID; PUBMED:9651579;

interacts with

 FSCN1BIOGRID; PUBMED:17353931;

interacts with

 FLNABIOGRID; PUBMED:12169691;

interacts with

 FLNABIOGRID; PUBMED:8674032;

interacts with

 TCEB3BIOGRID; PUBMED:12048197;

interacts with

 DVL2BIOGRID; PUBMED:20639871;

interacts with

 EP300BIOGRID; PUBMED:16678111;

interacts with

 CDO1BIOGRID; PUBMED:17353931;

interacts with

 CUL5BIOGRID; PUBMED:11384984;

interacts with

 DNAJA3BIOGRID; PUBMED:15805242;

interacts with

 CUL2BIOGRID; PUBMED:10421634;

interacts with

 CUL2BIOGRID; PUBMED:10587522;

interacts with

 CUL2BIOGRID; PUBMED:10823831;

interacts with

 CUL2BIOGRID; PUBMED:11384984;

interacts with

 CUL2BIOGRID; PUBMED:11865071;

interacts with

 CUL2BIOGRID; PUBMED:12048197;

interacts with

 CUL2BIOGRID; PUBMED:12604794;

interacts with

 CUL2BIOGRID; PUBMED:15966899;

interacts with

 CUL2BIOGRID; PUBMED:16611863;

interacts with

 CUL2BIOGRID; PUBMED:17132228;

interacts with

 CUL2BIOGRID; PUBMED:17353931;

interacts with

 CUL2BIOGRID; PUBMED:17439941;

interacts with

 CUL2BIOGRID; PUBMED:18173839;

interacts with

 CUL2BIOGRID; PUBMED:19030229;

interacts with

 CSTBBIOGRID; PUBMED:17353931;

interacts with

 CYBABIOGRID; PUBMED:17200123;

interacts with

 MCCBIOGRID; PUBMED:17353931;

interacts with

 CSTF3BIOGRID; PUBMED:17353931;

interacts with

 DGKZBIOGRID; PUBMED:17350623;

interacts with

 IMPDH2BIOGRID; PUBMED:17353931;

interacts with

 KAT2BBIOGRID; PUBMED:16678111;

interacts with

 RHOCBIOGRID; PUBMED:17353931;

interacts with

 RAB1BBIOGRID; PUBMED:17353931;

interacts with

 RBX1BIOGRID; PUBMED:12048197;

interacts with

 RBX1BIOGRID; PUBMED:12604794;

interacts with

 RBX1BIOGRID; PUBMED:16325183;

interacts with

 RBX1BIOGRID; PUBMED:17353931;

interacts with

 POLR2ABIOGRID; PUBMED:12604794;

interacts with

 POLR2ABIOGRID; PUBMED:18285459;

interacts with

 RIT1BIOGRID; PUBMED:19030229;

interacts with

 HNRNPA2B1BIOGRID; PUBMED:11517223;

interacts with

 RPA3BIOGRID; PUBMED:17353931;

interacts with

 PFASBIOGRID; PUBMED:17353931;

interacts with

 APRTBIOGRID; PUBMED:17353931;

interacts with

 JMJD1CBIOGRID; PUBMED:17353931;

interacts with

 PHF17BIOGRID; PUBMED:12169691;

interacts with

 PHF17BIOGRID; PUBMED:14973063;

interacts with

 VBP1BIOGRID; PUBMED:12169691;

interacts with

 VBP1BIOGRID; PUBMED:8674032;

interacts with

 PSMD13BIOGRID; PUBMED:17353931;

interacts with

 PPIBBIOGRID; PUBMED:17353931;

interacts with

 IREB2BIOGRID; PUBMED:15777842;

interacts with

 PSMB3BIOGRID; PUBMED:17353931;

interacts with

 PSMB1BIOGRID; PUBMED:17353931;

interacts with

 PSMC3BIOGRID; PUBMED:14556007;

interacts with

 PIN1BIOGRID; PUBMED:17353931;

interacts with

 TARSBIOGRID; PUBMED:17353931;

interacts with

 SAP130BIOGRID; PUBMED:18173839;

interacts with

 IARSBIOGRID; PUBMED:17353931;

interacts with

 STK16BIOGRID; PUBMED:17353931;

interacts with

 ZNF197BIOGRID; PUBMED:12682018;

interacts with

 USP20BIOGRID; PUBMED:12056827;

interacts with

 USP33BIOGRID; PUBMED:11739384;

interacts with

 MyogBIOGRID; PUBMED:17344222;

interacts with

 RPS9BIOGRID; PUBMED:17353931;

interacts with

 SAT2BIOGRID; PUBMED:17558023;

interacts with

 PAPSS2BIOGRID; PUBMED:17353931;

interacts with

 TP53BIOGRID; PUBMED:16678111;

interacts with

 OSR1BIOGRID; PUBMED:16511565;

interacts with

 CHMP2BBIOGRID; PUBMED:17353931;

interacts with

 CNTFBIOGRID; PUBMED:17353931;

interacts with

 NR4A3HPRD; PUBMED:18305400;

interacts with

 NR4A2HPRD; PUBMED:18305400;

interacts with

 LRRC41HPRD; PUBMED:11384984;

interacts with

 TCEB2HPRD; PUBMED:11384984;

interacts with

 TCEB2HPRD; PUBMED:11739384;

interacts with

 TCEB2HPRD; PUBMED:16503656;

interacts with

 TCEB2HPRD; PUBMED:7660122;

interacts with

 TCEB2HPRD; PUBMED:7660130;

interacts with

 TCEB2HPRD; PUBMED:9122164;

interacts with

 HIF1AHPRD; PUBMED:11504942;

interacts with

 HIF1AHPRD; PUBMED:14556007;

interacts with

 HIF3AHPRD; PUBMED:12538644;

interacts with

 EPAS1HPRD; PUBMED:10823831;

interacts with

 HIF1ANHPRD; PUBMED:11641274;

interacts with

 TCEB1HPRD; PUBMED:11384984;

interacts with

 TCEB1HPRD; PUBMED:11739384;

interacts with

 TCEB1HPRD; PUBMED:16503656;

interacts with

 TCEB1HPRD; PUBMED:7660122;

interacts with

 TCEB1HPRD; PUBMED:7660130;

interacts with

 TCEB1HPRD; PUBMED:9122164;

interacts with

 FLNAHPRD; PUBMED:8674032;

interacts with

 TCEB3HPRD; PUBMED:11384984;

interacts with

 CUL5HPRD; PUBMED:11384984;

interacts with

 CUL2HPRD; PUBMED:16325183;

interacts with

 CUL2HPRD; PUBMED:16503656;

interacts with

 CUL2HPRD; PUBMED:7660130;

interacts with

 CUL2HPRD; PUBMED:9122164;

interacts with

 RBX1HPRD; PUBMED:11384984;

interacts with

 RBX1HPRD; PUBMED:15601820;

interacts with

 RBX1HPRD; PUBMED:16325183;

interacts with

 RBX1HPRD; PUBMED:16503656;

interacts with

 HNRNPA2B1HPRD; PUBMED:11517223;

interacts with

 RNF139HPRD; PUBMED:12032852;

interacts with

 PHF17HPRD; PUBMED:12169691;

interacts with

 VBP1HPRD; PUBMED:8674032;

interacts with

 PSMC3HPRD; PUBMED:14556007;

interacts with

 SP1HPRD; PUBMED:9271438;

interacts with

 SOCS1HPRD; PUBMED:11384984;

interacts with

 WSB1HPRD; PUBMED:11384984;

interacts with

 ZNF197HPRD; PUBMED:12682018;

interacts with

 USP33HPRD; PUBMED:11739384;

interacts with

 FZR1INTACT; PUBMED:20802534;

interacts with

 PRKCZMINT; PUBMED:17350623;

interacts with

 TCEB2MINT; PUBMED:18323857;

interacts with

 HIF1AMINT; PUBMED:16511565;

interacts with

 HIF1AMINT; PUBMED:18323857;

interacts with

 TCEB1MINT; PUBMED:18323857;

interacts with

 FN1MINT; PUBMED:18323857;

interacts with

 CUL2MINT; PUBMED:18323857;

interacts with

 ZNF512BMINT; PUBMED:15231748;

Metabolic Interaction

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There is no record for VHL

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 TCEB2NCI_NATURE; PUBMED:10823831;PUBMED:11292862;PUBMED:10878807;PUBMED:19498162;PUBMED:10353251;

reacts with

 TCEB2NCI_NATURE; PUBMED:11292862;PUBMED:10823831;PUBMED:10878807;PUBMED:10353251;

reacts with

 TCEB2NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 HIF1ANCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 EPAS1NCI_NATURE; PUBMED:10823831;PUBMED:11292862;PUBMED:10878807;PUBMED:19498162;PUBMED:10353251;

reacts with

 EPAS1NCI_NATURE; PUBMED:11292862;PUBMED:10823831;PUBMED:10878807;PUBMED:10353251;

reacts with

 TCEB1NCI_NATURE; PUBMED:10823831;PUBMED:11292862;PUBMED:10878807;PUBMED:19498162;PUBMED:10353251;

reacts with

 TCEB1NCI_NATURE; PUBMED:11292862;PUBMED:10823831;PUBMED:10878807;PUBMED:10353251;

reacts with

 TCEB1NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 CUL2NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 RBX1NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 VHLNCI_NATURE; PUBMED:10823831;PUBMED:11292862;PUBMED:10878807;PUBMED:19498162;PUBMED:10353251;

reacts with

 VHLNCI_NATURE; PUBMED:11292862;PUBMED:10823831;PUBMED:10878807;PUBMED:10353251;

reacts with

 VHLNCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

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