Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

8312

Name

AXIN1

Synonymous

AXIN|PPP1R49;axin 1;AXIN1;axin 1

Definition

axin-1|axis inhibition protein 1|axis inhibitor 1|fused, mouse, homolog of|protein phosphatase 1, regulatory subunit 49

Position

16p13.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 MAP3K1BIOGRID; PUBMED:10829020;

interacts with

 MAP3K1BIOGRID; PUBMED:11884395;

interacts with

 LRP5BIOGRID; PUBMED:11336703;

interacts with

 LRP5BIOGRID; PUBMED:18632848;

interacts with

 DVL3BIOGRID; PUBMED:12805222;

interacts with

 CRMP1BIOGRID; PUBMED:16169070;

interacts with

 GSK3BBIOGRID; PUBMED:10228155;

interacts with

 GSK3BBIOGRID; PUBMED:12511557;

interacts with

 GSK3BBIOGRID; PUBMED:16199882;

interacts with

 GSK3BBIOGRID; PUBMED:18632848;

interacts with

 GSK3BBIOGRID; PUBMED:9734785;

interacts with

 GAKBIOGRID; PUBMED:16169070;

interacts with

 BTRCBIOGRID; PUBMED:10228155;

interacts with

 FAM123BBIOGRID; PUBMED:17510365;

interacts with

 EEF1A1BIOGRID; PUBMED:16169070;

interacts with

 DVL1BIOGRID; PUBMED:10428961;

interacts with

 DVL1BIOGRID; PUBMED:18632848;

interacts with

 DVL2BIOGRID; PUBMED:10829020;

interacts with

 DAB2BIOGRID; PUBMED:12805222;

interacts with

 DAXXBIOGRID; PUBMED:17210684;

interacts with

 CTNNB1BIOGRID; PUBMED:10228155;

interacts with

 CTNNB1BIOGRID; PUBMED:12421363;

interacts with

 CTNNB1BIOGRID; PUBMED:12805222;

interacts with

 CTNNB1BIOGRID; PUBMED:16199882;

interacts with

 CTNNB1BIOGRID; PUBMED:18632848;

interacts with

 CTNNB1BIOGRID; PUBMED:9734785;

interacts with

 CSNK1EBIOGRID; PUBMED:11884395;

interacts with

 CSNK1A1BIOGRID; PUBMED:11884395;

interacts with

 PPP2R5ABIOGRID; PUBMED:11297546;

interacts with

 ANP32ABIOGRID; PUBMED:16169070;

interacts with

 APCBIOGRID; PUBMED:10228155;

interacts with

 APCBIOGRID; PUBMED:16199882;

interacts with

 APCBIOGRID; PUBMED:9734785;

interacts with

 SMYD2BIOGRID; PUBMED:17353931;

interacts with

 UTP14ABIOGRID; PUBMED:16169070;

interacts with

 TSC2BIOGRID; PUBMED:12511557;

interacts with

 TSC1BIOGRID; PUBMED:12511557;

interacts with

 MAP3K4CELL_MAP; PUBMED:15262978;

interacts with

 LRP6CELL_MAP; PUBMED:12897152;

interacts with

 Senp2CELL_MAP; PUBMED:11997515;

interacts with

 GSK3BCELL_MAP; PUBMED:10228155;

interacts with

 GSK3BCELL_MAP; PUBMED:10535959;

interacts with

 GSK3BCELL_MAP; PUBMED:9501208;

interacts with

 BtrcCELL_MAP; PUBMED:10228155;

interacts with

 CTNNB1CELL_MAP; PUBMED:9501208;

interacts with

 PPP2R5BCELL_MAP; PUBMED:11297546;

interacts with

 APCCELL_MAP; PUBMED:10228155;

interacts with

 PPP2CACELL_MAP; PUBMED:10644691;

interacts with

 PPP2CACELL_MAP; PUBMED:9920888;PUBMED:10644691;

interacts with

 RUNX2CELL_MAP; PUBMED:15262978;

interacts with

 Csnk1eCELL_MAP; PUBMED:10535959;

interacts with

 MAP3K4HPRD; PUBMED:15262978;

interacts with

 NCK2HPRD; PUBMED:11557983;

interacts with

 LRP6HPRD; PUBMED:12897152;

interacts with

 LRP5HPRD; PUBMED:11336703;

interacts with

 AXIN2HPRD; PUBMED:16601693;

interacts with

 DVL3HPRD; PUBMED:12805222;

interacts with

 CRMP1HPRD; PUBMED:16169070;

interacts with

 GSK3BHPRD; PUBMED:12511557;

interacts with

 GSK3BHPRD; PUBMED:16199882;

interacts with

 GSK3BHPRD; PUBMED:9482734;

interacts with

 HNF4AHPRD; PUBMED:17289029;

interacts with

 GLIS2HPRD; PUBMED:17289029;

interacts with

 GAKHPRD; PUBMED:16169070;

interacts with

 EEF1A1HPRD; PUBMED:16169070;

interacts with

 DVL1HPRD; PUBMED:9482734;

interacts with

 DVL2HPRD; PUBMED:10829020;

interacts with

 CDH1HPRD; PUBMED:17289029;

interacts with

 DAB2HPRD; PUBMED:12805222;

interacts with

 DIXDC1HPRD; PUBMED:15262978;

interacts with

 CTNNB1HPRD; PUBMED:12000790;

interacts with

 CTNNB1HPRD; PUBMED:15327768;

interacts with

 CTNNB1HPRD; PUBMED:16199882;

interacts with

 CTNNB1HPRD; PUBMED:17289029;

interacts with

 CTNNB1HPRD; PUBMED:9482734;

interacts with

 CSNK1EHPRD; PUBMED:11487578;

interacts with

 RNF111HPRD; PUBMED:16601693;

interacts with

 ANP32AHPRD; PUBMED:16169070;

interacts with

 PPP2R5BHPRD; PUBMED:10698523;

interacts with

 APCHPRD; PUBMED:11297546;

interacts with

 APCHPRD; PUBMED:15327768;

interacts with

 APCHPRD; PUBMED:16199882;

interacts with

 APCHPRD; PUBMED:17289029;

interacts with

 PPP2CBHPRD; PUBMED:9920888;

interacts with

 PIAS1HPRD; PUBMED:12223491;

interacts with

 JUPHPRD; PUBMED:10488109;

interacts with

 PPP2CAHPRD; PUBMED:9920888;

interacts with

 SMAD6HPRD; PUBMED:16601693;

interacts with

 SMAD7HPRD; PUBMED:16601693;

interacts with

 SMAD2HPRD; PUBMED:11438668;

interacts with

 WISP1HPRD; PUBMED:16601693;

interacts with

 UTP14AHPRD; PUBMED:16169070;

interacts with

 TSC2HPRD; PUBMED:12511557;

interacts with

 SENP2HPRD; PUBMED:11997515;

interacts with

 SH3GL1HPRD; PUBMED:16169070;

interacts with

 RUNX2HPRD; PUBMED:15262978;

interacts with

 GSK3BINTACT; PUBMED:17601533;

interacts with

 TUBG1MINT; DOI:10.1038/embor.2009.45;

interacts with

 NINMINT; DOI:10.1038/embor.2009.45;

interacts with

 MYCMINT; DOI:10.1038/emboj.2008.279;

interacts with

 CRMP1MINT; PUBMED:16169070;

interacts with

 GSK3AMINT; PUBMED:17318175;

interacts with

 GSK3BMINT; DOI:10.1038/emboj.2008.279;

interacts with

 GSK3BMINT; PUBMED:17318191;

interacts with

 Rnf111MINT; PUBMED:16601693;

interacts with

 CTNNB1MINT; PUBMED:17318191;

interacts with

 CTNNB1MINT; PUBMED:19166851;

interacts with

 RNF111MINT; PUBMED:16601693;

interacts with

 PPP2R5AMINT; DOI:10.1038/emboj.2008.279;

interacts with

 ANP32AMINT; PUBMED:16169070;

interacts with

 APCMINT; DOI:10.1038/emboj.2008.279;

interacts with

 PPP2CAMINT; DOI:10.1038/emboj.2008.279;

interacts with

 PPP1CAMINT; PUBMED:17318175;

interacts with

 PIN1MINT; DOI:10.1038/emboj.2008.279;

interacts with

 SMAD7MINT; PUBMED:16601693;

interacts with

 UTP14AMINT; PUBMED:16169070;

Metabolic Interaction

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There is no record for AXIN1

Signaling Interaction

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Interaction Type

Interactor

Data Source

state change

 PPP2CACELL_MAP; PUBMED:10644691;

reacts with

 MAP3K4IMID; PUBMED:12878610;

reacts with

 MAP3K1IMID; PUBMED:11408485;PUBMED:12878610;

reacts with

 AXIN1IMID; PUBMED:11027605;PUBMED:10862053;PUBMED:10330181;

reacts with

 AXIN1IMID; PUBMED:11408485;PUBMED:12878610;

reacts with

 AXIN1IMID; PUBMED:12878610;

reacts with

 AXIN1IMID; PUBMED:9556553;PUBMED:9601641;PUBMED:9734785;

reacts with

 AXIN1IMID; PUBMED:9601641;PUBMED:10196136;PUBMED:9482734;PUBMED:9501208;

reacts with

 AXIN1IMID; PUBMED:9601641;PUBMED:10196136;PUBMED:9482734;PUBMED:9501208;PUBMED:11707456;

reacts with

 GSK3AIMID; PUBMED:9601641;PUBMED:10196136;PUBMED:9482734;PUBMED:9501208;PUBMED:11707456;

reacts with

 DVL1IMID; PUBMED:11027605;PUBMED:10862053;PUBMED:10330181;

reacts with

 CTNNB1IMID; PUBMED:9601641;PUBMED:10196136;PUBMED:9482734;PUBMED:9501208;

reacts with

 ANAPC1IMID; PUBMED:9556553;PUBMED:9601641;PUBMED:9734785;

state change

 TGFBR2NCI_NATURE; PUBMED:11438668;

state change

 TGFBR1NCI_NATURE; PUBMED:11438668;

reacts with

 CDH2NCI_NATURE; PUBMED:19075000;

reacts with

 LRP6NCI_NATURE; PUBMED:16341016;PUBMED:16341017;PUBMED:18077588;

reacts with

 LRP6NCI_NATURE; PUBMED:16341017;PUBMED:16890161;

reacts with

 LRP6NCI_NATURE; PUBMED:16341017;PUBMED:18077588;PUBMED:17569865;

reacts with

 LRP6NCI_NATURE; PUBMED:16341017;PUBMED:19309792;PUBMED:19107203;

reacts with

 LRP6NCI_NATURE; PUBMED:19107203;

reacts with

 LRP6NCI_NATURE; PUBMED:19309792;PUBMED:19107203;

reacts with

 LRP6NCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

state change

 LRP6NCI_NATURE; PUBMED:19107203;

state change

 LRP6NCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

reacts with

 LRP5NCI_NATURE; PUBMED:19075000;

reacts with

 AXIN1NCI_NATURE; PUBMED:10421629;PUBMED:11834740;PUBMED:12554650;PUBMED:10196136;PUBMED:10684251;PUBMED:19061640;PUBMED:16303557;PUBMED:15327768;

reacts with

 AXIN1NCI_NATURE; PUBMED:11438668;

reacts with

 AXIN1NCI_NATURE; PUBMED:11921277;

reacts with

 AXIN1NCI_NATURE; PUBMED:12554650;

reacts with

 AXIN1NCI_NATURE; PUBMED:12640114;PUBMED:17318191;

reacts with

 AXIN1NCI_NATURE; PUBMED:14657019;PUBMED:16601693;

reacts with

 AXIN1NCI_NATURE; PUBMED:15327768;

reacts with

 AXIN1NCI_NATURE; PUBMED:16341016;PUBMED:16341017;PUBMED:18077588;

reacts with

 AXIN1NCI_NATURE; PUBMED:16341017;PUBMED:16890161;

reacts with

 AXIN1NCI_NATURE; PUBMED:16341017;PUBMED:18077588;PUBMED:17569865;

reacts with

 AXIN1NCI_NATURE; PUBMED:16341017;PUBMED:19309792;PUBMED:19107203;

reacts with

 AXIN1NCI_NATURE; PUBMED:19075000;

reacts with

 AXIN1NCI_NATURE; PUBMED:19107203;

reacts with

 AXIN1NCI_NATURE; PUBMED:19309792;PUBMED:19107203;

reacts with

 AXIN1NCI_NATURE; PUBMED:19556239;PUBMED:11751573;

reacts with

 AXIN1NCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

reacts with

 AXIN1NCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

state change

 AXIN1NCI_NATURE; PUBMED:19107203;

state change

 AXIN1NCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

state change

 GSK3BNCI_NATURE; PUBMED:12554650;

state change

 GSK3BNCI_NATURE; PUBMED:15327768;

reacts with

 FZD5NCI_NATURE; PUBMED:16341016;PUBMED:16341017;PUBMED:18077588;

reacts with

 FZD5NCI_NATURE; PUBMED:16341017;PUBMED:16890161;

reacts with

 FZD5NCI_NATURE; PUBMED:16341017;PUBMED:18077588;PUBMED:17569865;

reacts with

 FZD5NCI_NATURE; PUBMED:16341017;PUBMED:19309792;PUBMED:19107203;

reacts with

 FZD5NCI_NATURE; PUBMED:19107203;

reacts with

 FZD5NCI_NATURE; PUBMED:19309792;PUBMED:19107203;

reacts with

 FZD5NCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

state change

 FZD5NCI_NATURE; PUBMED:19107203;

state change

 FZD5NCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

state change

 FRAT1NCI_NATURE; PUBMED:12554650;

state change

 DVL1NCI_NATURE; PUBMED:15327768;

reacts with

 CTNND1NCI_NATURE; PUBMED:19075000;

reacts with

 CTNNA1NCI_NATURE; PUBMED:19075000;

reacts with

 CTNNB1NCI_NATURE; PUBMED:10421629;PUBMED:11834740;PUBMED:12554650;PUBMED:10196136;PUBMED:10684251;PUBMED:19061640;PUBMED:16303557;PUBMED:15327768;

reacts with

 CTNNB1NCI_NATURE; PUBMED:11921277;

reacts with

 CTNNB1NCI_NATURE; PUBMED:12554650;

reacts with

 CTNNB1NCI_NATURE; PUBMED:12640114;PUBMED:17318191;

reacts with

 CTNNB1NCI_NATURE; PUBMED:15327768;

reacts with

 CTNNB1NCI_NATURE; PUBMED:19075000;

reacts with

 CTNNB1NCI_NATURE; PUBMED:19556239;PUBMED:11751573;

reacts with

 CTNNB1NCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

reacts with

 CTNNB1NCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

reacts with

 RNF111NCI_NATURE; PUBMED:14657019;PUBMED:16601693;

state change

 PPP2R5ANCI_NATURE; PUBMED:19556239;PUBMED:11751573;

state change

 PPP2R5DNCI_NATURE; PUBMED:15327768;

reacts with

 APCNCI_NATURE; PUBMED:10421629;PUBMED:11834740;PUBMED:12554650;PUBMED:10196136;PUBMED:10684251;PUBMED:19061640;PUBMED:16303557;PUBMED:15327768;

reacts with

 APCNCI_NATURE; PUBMED:11921277;

reacts with

 APCNCI_NATURE; PUBMED:12554650;

reacts with

 APCNCI_NATURE; PUBMED:12640114;PUBMED:17318191;

reacts with

 APCNCI_NATURE; PUBMED:15327768;

reacts with

 APCNCI_NATURE; PUBMED:19556239;PUBMED:11751573;

reacts with

 APCNCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

reacts with

 APCNCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

state change

 CSNK1G1NCI_NATURE; PUBMED:16341016;PUBMED:16341017;PUBMED:18077588;

state change

 CSNK1G1NCI_NATURE; PUBMED:16341017;PUBMED:19309792;PUBMED:19107203;

reacts with

 SMAD7NCI_NATURE; PUBMED:14657019;PUBMED:16601693;

reacts with

 WNT3ANCI_NATURE; PUBMED:16341016;PUBMED:16341017;PUBMED:18077588;

reacts with

 WNT3ANCI_NATURE; PUBMED:16341017;PUBMED:16890161;

reacts with

 WNT3ANCI_NATURE; PUBMED:16341017;PUBMED:18077588;PUBMED:17569865;

reacts with

 WNT3ANCI_NATURE; PUBMED:16341017;PUBMED:19309792;PUBMED:19107203;

reacts with

 WNT3ANCI_NATURE; PUBMED:19107203;

reacts with

 WNT3ANCI_NATURE; PUBMED:19309792;PUBMED:19107203;

reacts with

 WNT3ANCI_NATURE; PUBMED:9482734;PUBMED:10023673;PUBMED:14966280;PUBMED:12000790;

state change

 WNT3ANCI_NATURE; PUBMED:19107203;

state change

 WNT3ANCI_NATURE; PUBMED:9482734;PUBMED:9312064;PUBMED:10023673;PUBMED:10488109;PUBMED:14966280;PUBMED:12000790;

reacts with

 AXIN1REACTOME; PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:15327768;

reacts with

 AXIN1REACTOME; PUBMED:11955436;

reacts with

 AXIN1REACTOME; PUBMED:12000790;

reacts with

 AXIN1REACTOME; PUBMED:12554650;PUBMED:17143292;PUBMED:10092233;

reacts with

 AXIN1REACTOME; PUBMED:12628243;PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:17143292;

reacts with

 AXIN1REACTOME; PUBMED:12820959;

reacts with

 AXIN1REACTOME; PUBMED:16753179;PUBMED:15327769;PUBMED:15327768;

reacts with

 AXIN1REACTOME; PUBMED:17183061;

reacts with

 AXIN1REACTOME; PUBMED:9990852;PUBMED:10023660;

state change

 AXIN1REACTOME; PUBMED:11955436;

state change

 AXIN1REACTOME; PUBMED:12628243;PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:17143292;

reacts with

 BTRCREACTOME; PUBMED:12820959;

reacts with

 BTRCREACTOME; PUBMED:17183061;

reacts with

 BTRCREACTOME; PUBMED:9990852;PUBMED:10023660;

reacts with

 FAM123BREACTOME; PUBMED:17183061;

reacts with

 CUL1REACTOME; PUBMED:12820959;

reacts with

 CUL1REACTOME; PUBMED:17183061;

reacts with

 CUL1REACTOME; PUBMED:9990852;PUBMED:10023660;

reacts with

 CSNK1A1REACTOME; PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:15327768;

reacts with

 CSNK1A1REACTOME; PUBMED:11955436;

reacts with

 CSNK1A1REACTOME; PUBMED:12000790;

reacts with

 CSNK1A1REACTOME; PUBMED:12554650;PUBMED:17143292;PUBMED:10092233;

reacts with

 CSNK1A1REACTOME; PUBMED:12628243;PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:17143292;

reacts with

 CSNK1A1REACTOME; PUBMED:12820959;

reacts with

 CSNK1A1REACTOME; PUBMED:16753179;PUBMED:15327769;PUBMED:15327768;

reacts with

 CSNK1A1REACTOME; PUBMED:17183061;

reacts with

 CSNK1A1REACTOME; PUBMED:9990852;PUBMED:10023660;

state change

 CSNK1A1REACTOME; PUBMED:11955436;

state change

 CSNK1A1REACTOME; PUBMED:12628243;PUBMED:11707392;PUBMED:16753179;PUBMED:15327769;PUBMED:17143292;

reacts with

 SKP1REACTOME; PUBMED:12820959;

reacts with

 SKP1REACTOME; PUBMED:17183061;

reacts with

 SKP1REACTOME; PUBMED:9990852;PUBMED:10023660;

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