Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1030

Name

CDKN2B

Synonymous

CDK4I|INK4B|MTS2|P15|TP15|p15INK4b;cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4);CDKN2B;cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Definition

CDK inhibitory protein|CDK4B inhibitor|MTS-2|cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinases 4 and 6 binding protein|multiple tumor suppressor 2|p14-INK4b|p14_CDK inhibitor|p14_INK4B|p15 CDK inhibitor|p15-INK4b|p15_INK4B

Position

9p21

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Cdk6(h) + p15INK4b(h) <==> Cdk6(h):p15INK4b(h) (binding)
Cdk4(h) + p15INK4b(h) <==> Cdk4(h):p15INK4b(h) (binding)
p15INK4b(h) + MAGE11(h) <==> p15INK4b(h):MAGE11(h) (binding)
CDKN2B(h) --> p15INK4b(h) (expression).
TGFbeta1(h) --> p15INK4b(h) (increase of abundance)
TGFbeta1(m.s.) --> p15INK4b(h) (increase of abundance)
TGFbeta2(m.s.) --> p15INK4b(h) (increase of abundance)
p15INK4b(h) + Cdk4(h) <==> p15INK4b(h):Cdk4(h) (binding)
p15INK4b(h) + Cdk6(h) <==> p15INK4b(h):Cdk6(h) (binding)
p15INK4b(h) --/ p21Cip1(h) (decrease of abundance)
CDKN2B(h) --> p15INK4b(h) (expression).
Smad4(m.s.) --> p15INK4b(h) (increase of abundance)

Post Transcriptional Modification From dbPTM

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There is no record for CDKN2B

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr9

Promoter: 21998812 - 22000812Agilent_014791

chr9

Promoter: 21998812 - 22000812GoldenGate_Methylation_Cancer_Panel_I

chr9

Promoter: 21998812 - 22000812GoldenGate_Methylation_Cancer_Panel_I

chr9

Promoter: 21998812 - 22000812GSE27584

chr9

Promoter: 21998812 - 22000812GSE27584

chr9

Promoter: 21998812 - 22000812Agilent_014791_44K

chr9

Promoter: 21998812 - 22000812E-GEOD-20553

chr9

Promoter: 21998812 - 22000812E-GEOD-20553

chr9

Promoter: 21998812 - 22000812PMID:20064646

chr9

Promoter: 21998812 - 22000812PMID:20064646

chr9

Promoter: 21998812 - 22000812PMID:11413509

chr9

Promoter: 21998812 - 22000812PMID:11413509

chr9

Promoter: 21998812 - 22000812PMID:14513284

chr9

Promoter: 21998812 - 22000812PMID:14513284

chr9

Promoter: 21998812 - 22000812PMID:15495254

chr9

Promoter: 21998812 - 22000812PMID:15495254

chr9

Promoter: 21998812 - 22000812PMID:12970781

chr9

Promoter: 21998812 - 22000812PMID:12970781

chr9

Promoter: 21998812 - 22000812PMID:10706859

chr9

Promoter: 21998812 - 22000812PMID:10706859

chr9

Promoter: 21998812 - 22000812PMID:10634644

chr9

Promoter: 21998812 - 22000812PMID:10634644

chr9

Promoter: 21998812 - 22000812PMID:11532526

chr9

Promoter: 21998812 - 22000812PMID:11532526

chr9

Promoter: 21998812 - 22000812PMID:15863205

chr9

Promoter: 21998812 - 22000812PMID:15863205

chr9

Promoter: 21998812 - 22000812PMID:11877040

chr9

Promoter: 21998812 - 22000812PMID:11877040

chr9

Promoter: 21998812 - 22000812PMID:11283136

chr9

Promoter: 21998812 - 22000812PMID:11283136

chr9

Promoter: 21998812 - 22000812PMID:12899712

chr9

Promoter: 21998812 - 22000812PMID:12899712

chr9

Promoter: 21998812 - 22000812PMID:15198948

chr9

Promoter: 21998812 - 22000812PMID:15198948

chr9

Promoter: 21998812 - 22000812PMID:16192589

chr9

Promoter: 21998812 - 22000812PMID:16192589

chr9

Promoter: 21998812 - 22000812PMID:9399648

chr9

Promoter: 21998812 - 22000812PMID:9399648

chr9

Promoter: 21998812 - 22000812PMID:15475071

chr9

Promoter: 21998812 - 22000812PMID:15475071

chr9

Promoter: 21998812 - 22000812PMID:16682076

chr9

Promoter: 21998812 - 22000812PMID:16682076

chr9

Promoter: 21998812 - 22000812PMID:10764143

chr9

Promoter: 21998812 - 22000812PMID:10764143

chr9

Promoter: 21998812 - 22000812PMID:11167795

chr9

Promoter: 21998812 - 22000812PMID:11167795

chr9

Promoter: 21998812 - 22000812PMID:15755284

chr9

Promoter: 21998812 - 22000812PMID:15755284

chr9

Promoter: 21998812 - 22000812PMID:9269757

chr9

Promoter: 21998812 - 22000812PMID:9269757

chr9

Promoter: 21998812 - 22000812PMID:11584062

chr9

Promoter: 21998812 - 22000812PMID:11584062

chr9

Promoter: 21998812 - 22000812PMID:16343268

chr9

Promoter: 21998812 - 22000812PMID:16343268

chr9

Promoter: 21998812 - 22000812PMID:12114423

chr9

Promoter: 21998812 - 22000812PMID:12114423

chr9

Promoter: 21998812 - 22000812PMID:12548613

chr9

Promoter: 21998812 - 22000812PMID:12548613

chr9

Promoter: 21998812 - 22000812PMID:16565223

chr9

Promoter: 21998812 - 22000812PMID:16565223

chr9

Promoter: 21998812 - 22000812PMID:11721363

chr9

Promoter: 21998812 - 22000812PMID:11721363

chr9

Promoter: 21998812 - 22000812PMID:12150726

chr9

Promoter: 21998812 - 22000812PMID:12150726

chr9

Promoter: 21998812 - 22000812PMID:17056112

chr9

Promoter: 21998812 - 22000812PMID:17056112

chr9

Promoter: 21998812 - 22000812PMID:12750706

chr9

Promoter: 21998812 - 22000812PMID:12750706

chr9

Promoter: 21998812 - 22000812PMID:10779450

chr9

Promoter: 21998812 - 22000812PMID:10779450

chr9

Promoter: 21998812 - 22000812PMID:9473234

chr9

Promoter: 21998812 - 22000812PMID:9473234

chr9

Promoter: 21998812 - 22000812PMID:10477703

chr9

Promoter: 21998812 - 22000812PMID:10477703

chr9

Promoter: 21998812 - 22000812PMID:12213729

chr9

Promoter: 21998812 - 22000812PMID:12213729

chr9

Promoter: 21998812 - 22000812PMID:16406514

chr9

Promoter: 21998812 - 22000812PMID:16406514

chr9

Promoter: 21998812 - 22000812PMID:12060387

chr9

Promoter: 21998812 - 22000812PMID:12060387

chr9

Promoter: 21998812 - 22000812PMID:15897551

chr9

Promoter: 21998812 - 22000812PMID:15897551

chr9

Promoter: 21998812 - 22000812PMID:11786399

chr9

Promoter: 21998812 - 22000812PMID:11786399

chr9

Promoter: 21998812 - 22000812PMID:9639423

chr9

Promoter: 21998812 - 22000812PMID:9639423

chr9

Promoter: 21998812 - 22000812PMID:16858686

chr9

Promoter: 21998812 - 22000812PMID:16858686

chr9

Promoter: 21998812 - 22000812PMID:12447702

chr9

Promoter: 21998812 - 22000812PMID:12447702

chr9

Promoter: 21998812 - 22000812PMID:15892004

chr9

Promoter: 21998812 - 22000812PMID:15892004

chr9

Promoter: 21998812 - 22000812PMID:11764089

chr9

Promoter: 21998812 - 22000812PMID:11764089

chr9

Promoter: 21998812 - 22000812PMID:11487055

chr9

Promoter: 21998812 - 22000812PMID:11487055

chr9

Promoter: 21998812 - 22000812PMID:14581362

chr9

Promoter: 21998812 - 22000812PMID:14581362

chr9

Promoter: 21998812 - 22000812PMID:14636164

chr9

Promoter: 21998812 - 22000812PMID:14636164

chr9

Promoter: 21998812 - 22000812PMID:17216555

chr9

Promoter: 21998812 - 22000812PMID:17216555

chr9

Promoter: 21998812 - 22000812PMID:15112341

chr9

Promoter: 21998812 - 22000812PMID:15112341

chr9

Promoter: 21998812 - 22000812PMID:12937151

chr9

Promoter: 21998812 - 22000812PMID:12937151

chr9

Promoter: 21998812 - 22000812PMID:16764763

chr9

Promoter: 21998812 - 22000812PMID:16764763

chr9

Promoter: 21998812 - 22000812PMID:10999738

chr9

Promoter: 21998812 - 22000812PMID:10999738

chr9

Promoter: 21998812 - 22000812PMID:12143052

chr9

Promoter: 21998812 - 22000812PMID:12143052

chr9

Promoter: 21998812 - 22000812PMID:17289889

chr9

Promoter: 21998812 - 22000812PMID:17289889

chr9

Promoter: 21998812 - 22000812PMID:15467712

chr9

Promoter: 21998812 - 22000812PMID:15467712

chr9

Promoter: 21998812 - 22000812PMID:15197802

chr9

Promoter: 21998812 - 22000812PMID:15197802

chr9

Promoter: 21998812 - 22000812PMID:15109538

chr9

Promoter: 21998812 - 22000812PMID:15109538

chr9

Promoter: 21998812 - 22000812PMID:12578664

chr9

Promoter: 21998812 - 22000812PMID:12578664

chr9

Promoter: 21998812 - 22000812PMID:12906163

chr9

Promoter: 21998812 - 22000812PMID:12906163

chr9

Promoter: 21998812 - 22000812PMID:11243384

chr9

Promoter: 21998812 - 22000812PMID:11243384

chr9

Promoter: 21998812 - 22000812PMID:15260845

chr9

Promoter: 21998812 - 22000812PMID:15260845

chr9

Promoter: 21998812 - 22000812PMID:11445839

chr9

Promoter: 21998812 - 22000812PMID:11445839

chr9

Promoter: 21998812 - 22000812PMID:11895880

chr9

Promoter: 21998812 - 22000812PMID:11895880

chr9

Promoter: 21998812 - 22000812PMID:15189501

chr9

Promoter: 21998812 - 22000812PMID:15189501

chr9

Promoter: 21998812 - 22000812PMID:15526363

chr9

Promoter: 21998812 - 22000812PMID:15526363

chr9

Promoter: 21998812 - 22000812PMID:16872319

chr9

Promoter: 21998812 - 22000812PMID:16872319

chr9

Promoter: 21998812 - 22000812PMID:15389252

chr9

Promoter: 21998812 - 22000812PMID:15389252

chr9

Promoter: 21998812 - 22000812PMID:14719065

chr9

Promoter: 21998812 - 22000812PMID:14719065

chr9

Promoter: 21998812 - 22000812PMID:12448005

chr9

Promoter: 21998812 - 22000812PMID:12448005

chr9

Promoter: 21998812 - 22000812PMID:11413518

chr9

Promoter: 21998812 - 22000812PMID:11413518

chr9

Promoter: 21998812 - 22000812PMID:12060614

chr9

Promoter: 21998812 - 22000812PMID:12060614

chr9

Promoter: 21998812 - 22000812PMID:17369979

chr9

Promoter: 21998812 - 22000812PMID:17369979

chr9

Promoter: 21998812 - 22000812PMID:12767073

chr9

Promoter: 21998812 - 22000812PMID:12767073

chr9

Promoter: 21998812 - 22000812PMID:15073117

chr9

Promoter: 21998812 - 22000812PMID:15073117

chr9

Promoter: 21998812 - 22000812PMID:12632081

chr9

Promoter: 21998812 - 22000812PMID:12632081

chr9

Promoter: 21998812 - 22000812PMID:17177027

chr9

Promoter: 21998812 - 22000812PMID:17177027

chr9

Promoter: 21998812 - 22000812PMID:16000597

chr9

Promoter: 21998812 - 22000812PMID:16000597

chr9

Promoter: 21998812 - 22000812PMID:12376481

chr9

Promoter: 21998812 - 22000812PMID:12376481

chr9

Promoter: 21998812 - 22000812PMID:10537333

chr9

Promoter: 21998812 - 22000812PMID:10537333

chr9

Promoter: 21998812 - 22000812PMID:12374684

chr9

Promoter: 21998812 - 22000812PMID:12374684

chr9

Promoter: 21998812 - 22000812PMID:12672028

chr9

Promoter: 21998812 - 22000812PMID:12672028

chr9

Promoter: 21998812 - 22000812PMID:12932666

chr9

Promoter: 21998812 - 22000812PMID:12932666

chr9

Promoter: 21998812 - 22000812PMID:15221997

chr9

Promoter: 21998812 - 22000812PMID:15221997

chr9

Promoter: 21998812 - 22000812PMID:15154012

chr9

Promoter: 21998812 - 22000812PMID:15154012

chr9

Promoter: 21998812 - 22000812PMID:11839665

chr9

Promoter: 21998812 - 22000812PMID:11839665

chr9

Promoter: 21998812 - 22000812PMID:15713962

chr9

Promoter: 21998812 - 22000812PMID:15713962

chr9

Promoter: 21998812 - 22000812PMID:15892297

chr9

Promoter: 21998812 - 22000812PMID:15892297

chr9

Promoter: 21998812 - 22000812PMID:16537562

chr9

Promoter: 21998812 - 22000812PMID:16537562

chr9

Promoter: 21998812 - 22000812PMID:15447999

chr9

Promoter: 21998812 - 22000812PMID:15447999


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