|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10817 |
Name | FRS3 |
Synonymous | FRS2B|FRS2beta|SNT-2|SNT2;fibroblast growth factor receptor substrate 3;FRS3;fibroblast growth factor receptor substrate 3 |
Definition | FGFR substrate 3|FGFR-signaling adaptor SNT2|FRS2-beta|suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) |
Position | 6p21.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
FRS3(h) + TrkA-II(r) <==> FRS3(h):TrkA-II(r) (binding) | FRS3(h) + trkB-GP145(r) <==> FRS3(h):trkB-GP145(r) (binding) | FRS3(h) + trkC(r) <==> FRS3(h):trkC(r) (binding) | FRS3(h) + ATP --TrkA-II(r)--> FRS3(h){pY} + ADP (phosphorylation) | FRS3(h) + ATP --trkB-GP145(r)--> FRS3(h){pY} + ADP (phosphorylation) | FRS3(h) + ATP --trkC(r)--> FRS3(h){pY} + ADP (phosphorylation) | SHP-2(r) + Grb-2(r) + FRS3(h) <==> SHP-2(r):Grb-2(r):FRS3(h) (binding) | Grb-2(mo) + SHP-2(mo) + FRS3(h) <==> Grb-2(mo):SHP-2(mo):FRS3(h) (binding) | FRS3(h) + ATP --> FRS3(h){pY} + ADP (phosphorylation) | FRS3(h) --> FRS3(h) (expression). | FRS3(h) --> FRS3(h) (expression). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
|
Location (AA) |
PTM type |
Literature |
Database |
2 | N-myristoyl glycine (Probable). | Swiss-Prot 53.0 |
|---|
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr6 |
Promoter: 41855108 - 41857108 | GSE27584 |
chr6 |
Promoter: 41855108 - 41857108 | Agilent_014791_44K |