Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1487

Name

CTBP1

Synonymous

BARS;C-terminal binding protein 1;CTBP1;C-terminal binding protein 1

Definition

C-terminal-binding protein 1|brefeldin A-ribosylated substrate

Position

4p16

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Evi-1(h) + CtBP1(h) <==> Evi-1(h):CtBP1(h) (binding)
CtBP1(h) + TCF-4(h) <==> CtBP1(h):TCF-4(h) (binding)
CtBP1(h) --> AXIN2(h) (transactivation)
CtBP1(h) + mdm2(h) <==> CtBP1(h):mdm2(h) (binding)
NADH + CtBP1(h) <==> NADH:CtBP1(h) (binding)
NAD+ + CtBP1(h) <==> NAD+:CtBP1(h) (binding)
2 CtBP1(h) <==> (CtBP1(h))2 (binding)
CtBP1(h) + E1A-243R(AD2) <==> CtBP1(h):E1A-243R(AD2) (binding)
CtBP1(h) + CtIP(m) <==> CtBP1(h):CtIP(m) (binding)
CtBP1(h) + KLF3(m) <==> CtBP1(h):KLF3(m) (binding)
CtBP1(h) + ZEB(m) <==> CtBP1(h):ZEB(m) (binding)
CtBP1(h) + RIP140(m) <==> CtBP1(h):RIP140(m) (binding)
CtBP1(h) + RIP140(h) <==> CtBP1(h):RIP140(h) (binding)
CtBP1(h) + RIP140(mo) <==> CtBP1(h):RIP140(mo) (binding)
CtBP1(h) + sumo1(h) --> CtBP1(h){sumo} (sumoylation)
CtBP1(h) + p16INK4a-p19(m) <==> CtBP1(h):p16INK4a-p19(m) (binding)
Smad6(h) + CtBP1(h) <==> Smad6(h):CtBP1(h) (binding)
CtBP1(h) + HIC-1-isoform2(h) <==> CtBP1(h):HIC-1-isoform2(h) (binding)
CTBP1(h) --> CtBP1(h) (expression).
CtBP1(h) + TGIF(h) <==> CtBP1(h):TGIF(h) (binding)
CtBP1(h) + TGIF2(h) <==> CtBP1(h):TGIF2(h) (binding)
TGIF1-isoform1(m) + CtBP1(h) <==> TGIF1-isoform1(m):CtBP1(h) (binding)
TGIF1-isoform1(m) + CtBP1(h) + HDAC1(h) <==> TGIF1-isoform1(m):CtBP1(h):HDAC1(h) (binding)
Smad2(m.s.) + CtBP1(h) + TGIF1-isoform1(m) <==> Smad2(m.s.):CtBP1(h):TGIF1-isoform1(m) (binding)
Ikaros(m) + CtBP1(h) <==> Ikaros(m):CtBP1(h) (binding)
CtBP1(h) + Ikaros-1(h) <==> CtBP1(h):Ikaros-1(h) (binding)
CtBP1(h) + Ikaros-1(m.s.) <==> CtBP1(h):Ikaros-1(m.s.) (binding)
Ikaros-isoform3(m) + CtBP1(h) <==> Ikaros-isoform3(m):CtBP1(h) (binding)
CtBP1(h) + Ikaros-isoform2(m) <==> CtBP1(h):Ikaros-isoform2(m) (binding)
Ikaros-isoform1(m) + CtBP1(h) <==> Ikaros-isoform1(m):CtBP1(h) (binding)
Aiolos(m.s.) + Ikaros-1(m.s.) + CtBP1(h) <==> Aiolos(m.s.):Ikaros-1(m.s.):CtBP1(h) (binding)
sin3a(h) + CtBP1(h) <==> sin3a(h):CtBP1(h) (binding)
hdac2(h) + CtBP1(h) <==> hdac2(h):CtBP1(h) (binding)
CtBP1(h) + hdac2(m.s.) <==> CtBP1(h):hdac2(m.s.) (binding)
CTBP1(h) --> CtBP1(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

422Phosphoserine (by HIPK2).Swiss-Prot 53.0
428Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr4

Promoter: 1232408 - 1234408GSE27584

chr4

Promoter: 1232408 - 1234408GSE27584

chr4

Promoter: 1232408 - 1234408Agilent_014791_44K

chr4

Promoter: 1232408 - 1234408Agilent_014791


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