Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1915

Name

EEF1A1

Synonymous

CCS-3|CCS3|EE1A1|EEF-1|EEF1A|EF-Tu|EF1A|GRAF-1EF|HNGC:16303|LENG7|PTI1|eEF1A-1;eukaryotic translation elongation factor 1 alpha 1;EEF1A1;eukaryotic translation elongation factor 1 alpha 1

Definition

CTCL tumor antigen|EF-1-alpha-1|EF1a-like protein|cervical cancer suppressor 3|elongation factor 1 alpha subunit|elongation factor 1-alpha 1|elongation factor Tu|eukaryotic elongation factor 1 A-1|eukaryotic translation elongation factor 1 alpha 1-like 14

Position

6q14.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

dlc1-isoform1(h) + EEF1A(h) <==> dlc1-isoform1(h):EEF1A(h) (binding)
SK1(h) + EEF1A(h) <==> SK1(h):EEF1A(h) (binding)
EEF1A(h) + SK1(h){pS225} <==> EEF1A(h):SK1(h){pS225} (binding)
EEF1A(h) + ATP --p70S6K1(m.s.)--> EEF1A(h){p} + ADP (phosphorylation)
EEF1A(h) + sphingosine kinase 2(h) <==> EEF1A(h):sphingosine kinase 2(h) (binding)
EEF1A1(h) --> EEF1A(h) (expression).
GADD45-gamma(h) + EEF1A(h) <==> GADD45-gamma(h):EEF1A(h) (binding)
APLP1(h) + EEF1A(h) <==> APLP1(h):EEF1A(h) (binding)
MGMT(h) + EEF1A(h) <==> MGMT(h):EEF1A(h) (binding)
EEF1A(h) + Rrp41(h) <==> EEF1A(h):Rrp41(h) (binding)
EEF1A(h) + HCV-NS4A-1B(HCV1B) <==> EEF1A(h):HCV-NS4A-1B(HCV1B) (binding)
bbs1(h) + EEF1A(h) <==> bbs1(h):EEF1A(h) (binding)
bbs2(h) + EEF1A(h) <==> bbs2(h):EEF1A(h) (binding)
bbs4(h) + EEF1A(h) <==> bbs4(h):EEF1A(h) (binding)
EEF1A(h) + dlc1-isoform1(h) <==> EEF1A(h):dlc1-isoform1(h) (binding)
Hsp10(h) + EEF1A(h) <==> Hsp10(h):EEF1A(h) (binding)
laminin-alpha4(h) + EEF1A(h) <==> laminin-alpha4(h):EEF1A(h) (binding)
platelet-activating factor acetylhydrolase IB subunit gamma(h) + EEF1A(h) <==> platelet-activating factor acetylhydrolase IB subunit gamma(h):EEF1A(h) (binding)
CAP3(h) + EEF1A(h) <==> CAP3(h):EEF1A(h) (binding)
S9(h) + EEF1A(h) <==> S9(h):EEF1A(h) (binding)
RPA2(h) + EEF1A(h) <==> RPA2(h):EEF1A(h) (binding)
RRP1(h) + EEF1A(h) <==> RRP1(h):EEF1A(h) (binding)
PARC(h) + EEF1A(h) <==> PARC(h):EEF1A(h) (binding)
ZNF-24(h) + EEF1A(h) <==> ZNF-24(h):EEF1A(h) (binding)
dleu1(h) + EEF1A(h) <==> dleu1(h):EEF1A(h) (binding)
Ari-2(h) + EEF1A(h) <==> Ari-2(h):EEF1A(h) (binding)
Lsm3(h) + EEF1A(h) <==> Lsm3(h):EEF1A(h) (binding)
BTBD2(h) + EEF1A(h) <==> BTBD2(h):EEF1A(h) (binding)
Cks2(h) + EEF1A(h) <==> Cks2(h):EEF1A(h) (binding)
PTN4(h) + EEF1A(h) <==> PTN4(h):EEF1A(h) (binding)
TAF(II)31(h) + EEF1A(h) <==> TAF(II)31(h):EEF1A(h) (binding)
TBPA(h) + EEF1A(h) <==> TBPA(h):EEF1A(h) (binding)
axin(h) + EEF1A(h) <==> axin(h):EEF1A(h) (binding)
LC8(h) + EEF1A(h) <==> LC8(h):EEF1A(h) (binding)
eif3s5(h) + EEF1A(h) <==> eif3s5(h):EEF1A(h) (binding)
rsrc1(h) + EEF1A(h) <==> rsrc1(h):EEF1A(h) (binding)
Ubiquilin-4(h) + EEF1A(h) <==> Ubiquilin-4(h):EEF1A(h) (binding)
tmprss3(h) + EEF1A(h) <==> tmprss3(h):EEF1A(h) (binding)
EEF1A(h) + profilin2(h) <==> EEF1A(h):profilin2(h) (binding)
Fas(h) + EEF1A(h) <==> Fas(h):EEF1A(h) (binding)
DMNT2(h) + EEF1A(h) <==> DMNT2(h):EEF1A(h) (binding)
Glycodelin(h) + EEF1A(h) <==> Glycodelin(h):EEF1A(h) (binding)
DNA polymerase epsilon subunit 2(h) + EEF1A(h) <==> DNA polymerase epsilon subunit 2(h):EEF1A(h) (binding)
RPB3(h) + EEF1A(h) <==> RPB3(h):EEF1A(h) (binding)
psg9(h) + EEF1A(h) <==> psg9(h):EEF1A(h) (binding)
RFC5(h) + EEF1A(h) <==> RFC5(h):EEF1A(h) (binding)
Intersectin1(h) + EEF1A(h) <==> Intersectin1(h):EEF1A(h) (binding)
TRAPA(h) + EEF1A(h) <==> TRAPA(h):EEF1A(h) (binding)
STE(h) + EEF1A(h) <==> STE(h):EEF1A(h) (binding)
TGIF(h) + EEF1A(h) <==> TGIF(h):EEF1A(h) (binding)
ASPP2(h) + EEF1A(h) <==> ASPP2(h):EEF1A(h) (binding)
bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1(h) + EEF1A(h) <==> bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1(h):EEF1A(h) (binding)
p31-comet(h) + EEF1A(h) <==> p31-comet(h):EEF1A(h) (binding)
rnf10(h) + EEF1A(h) <==> rnf10(h):EEF1A(h) (binding)
Cox17(h) + EEF1A(h) <==> Cox17(h):EEF1A(h) (binding)
pqbp1(h) + EEF1A(h) <==> pqbp1(h):EEF1A(h) (binding)
hbxip(h) + EEF1A(h) <==> hbxip(h):EEF1A(h) (binding)
stathmin 2(h) + EEF1A(h) <==> stathmin 2(h):EEF1A(h) (binding)
tmsb4x(m) + EEF1A(h) <==> tmsb4x(m):EEF1A(h) (binding)
MRPS32(h) + EEF1A(h) <==> MRPS32(h):EEF1A(h) (binding)
sdhaf2(h) + EEF1A(h) <==> sdhaf2(h):EEF1A(h) (binding)
CNR1(h) + EEF1A(h) <==> CNR1(h):EEF1A(h) (binding)
ankrd24(h) + EEF1A(h) <==> ankrd24(h):EEF1A(h) (binding)
EEF1A(h) + SK1(h) <==> EEF1A(h):SK1(h) (binding)
EEF1A(h) + SK1(h) <==> EEF1A(h):SK1(h) (binding)
EEF1A1(h) --> EEF1A(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

29Phosphotyrosine.Swiss-Prot 53.0
36N6,N6,N6-trimethyllysine (By similarity).Swiss-Prot 53.0
55N6,N6-dimethyllysine (By similarity).Swiss-Prot 53.0
79N6,N6,N6-trimethyllysine (By similarity).Swiss-Prot 53.0
165N6,N6-dimethyllysine (By similarity).Swiss-Prot 53.0
318N6,N6,N6-trimethyllysine; alternate (Bysimilarity).Swiss-Prot 53.0
318N6-acetyllysine; alternate.Swiss-Prot 53.0
141Phosphotyrosine16497976Phospho.ELM 6.0
29Phosphotyrosine16497976Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr6

Promoter: 74286976 - 74288976Agilent_014791

chr6

Promoter: 74286976 - 74288976GSE27584


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