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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 2242 |
Name | FES |
Synonymous | FPS;feline sarcoma oncogene;FES;feline sarcoma oncogene |
Definition | Oncogene FES, feline sarcoma virus|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|feline sarcoma/Fujinami avian sarcoma oncogene homolog|p93c-fes|proto-oncogene c-Fes|proto-oncogene c-Fps|proto- |
Position | 15q26.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
Fes(h) + STAT1(h) <==> Fes(h):STAT1(h) (binding) | Fes(h) + STAT3(h) <==> Fes(h):STAT3(h) (binding) | psmd13(h) + Fes(h) <==> psmd13(h):Fes(h) (binding) | FES(h) --> Fes(h) (expression). | STAT3(m) + NTP --Fes(h)--> STAT3(m){pY} + NDP (phosphorylation) | STAT5A(m) + NTP --Fes(h)--> STAT5A(m){pY} + NDP (phosphorylation) | ErbB1-p170(h){pY998} + Fes(h) <==> ErbB1-p170(h){pY998}:Fes(h) (binding) | ErbB2(h) + Fes(h) <==> ErbB2(h):Fes(h) (binding) | FES(h) --> Fes(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) |
PTM type |
Literature |
Database |
713 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 811 | Phosphotyrosine (Fes) | 7687763 | Phospho.ELM 6.0 | 713 | Phosphotyrosine (Fes) | 8663427 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr15 |
Promoter: 89227213 - 89229213 | Agilent_014791 |
chr15 |
Promoter: 89227213 - 89229213 | GoldenGate_Methylation_Cancer_Panel_I |
chr15 |
Promoter: 89227213 - 89229213 | GSE27584 |
chr15 |
Promoter: 89227213 - 89229213 | Agilent_014791_44K |
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