Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2242

Name

FES

Synonymous

FPS;feline sarcoma oncogene;FES;feline sarcoma oncogene

Definition

Oncogene FES, feline sarcoma virus|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|feline sarcoma/Fujinami avian sarcoma oncogene homolog|p93c-fes|proto-oncogene c-Fes|proto-oncogene c-Fps|proto-

Position

15q26.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Fes(h) + STAT1(h) <==> Fes(h):STAT1(h) (binding)
Fes(h) + STAT3(h) <==> Fes(h):STAT3(h) (binding)
psmd13(h) + Fes(h) <==> psmd13(h):Fes(h) (binding)
FES(h) --> Fes(h) (expression).
STAT3(m) + NTP --Fes(h)--> STAT3(m){pY} + NDP (phosphorylation)
STAT5A(m) + NTP --Fes(h)--> STAT5A(m){pY} + NDP (phosphorylation)
ErbB1-p170(h){pY998} + Fes(h) <==> ErbB1-p170(h){pY998}:Fes(h) (binding)
ErbB2(h) + Fes(h) <==> ErbB2(h):Fes(h) (binding)
FES(h) --> Fes(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

713Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
811Phosphotyrosine (Fes)7687763Phospho.ELM 6.0
713Phosphotyrosine (Fes)8663427Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr15

Promoter: 89227213 - 89229213Agilent_014791

chr15

Promoter: 89227213 - 89229213GoldenGate_Methylation_Cancer_Panel_I

chr15

Promoter: 89227213 - 89229213GSE27584

chr15

Promoter: 89227213 - 89229213Agilent_014791_44K


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