Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2909

Name

ARHGAP35

Synonymous

GRF-1|GRLF1|P190-A|P190A|p190ARhoGAP|p190RhoGAP;Rho GTPase activating protein 35;ARHGAP35;Rho GTPase activating protein 35

Definition

glucocorticoid receptor DNA binding factor 1|glucocorticoid receptor DNA-binding factor 1|glucocorticoid receptor repression factor 1|rho GAP p190A|rho GTPase-activating protein 35

Position

19q13.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

SPIN90(h) + p190RhoGAP(h) <==> SPIN90(h):p190RhoGAP(h) (binding)
RasGAP(mo) + p190RhoGAP(h) <==> RasGAP(mo):p190RhoGAP(h) (binding)
p190RhoGAP(h) --> paxillin(mo):RasGAP(mo) (decrease of binding)
Pyk2(h) + p190RhoGAP(h) <==> Pyk2(h):p190RhoGAP(h) (binding)
p190RhoGAP(h) + ATP --> p190RhoGAP(h){pY} + ADP (phosphorylation)
GRLF1(h) --> p190RhoGAP(h) (expression).
p190RhoGAP(h) --/ NR3C1(h) (DNA binding; transrepression).
GRLF1(h) --> p190RhoGAP(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

685Phosphothreonine.Swiss-Prot 53.0
773Phosphoserine (By similarity).Swiss-Prot 53.0
980Phosphoserine (By similarity).Swiss-Prot 53.0
1105Phosphotyrosine.Swiss-Prot 53.0
1134Phosphoserine.Swiss-Prot 53.0
1179Phosphoserine.Swiss-Prot 53.0
1134Phosphoserine15302935Phospho.ELM 6.0
1179Phosphoserine15302935Phospho.ELM 6.0
1105Phosphotyrosine (Src)9819392;11309200;15592455Phospho.ELM 6.0
1150Phosphoserine16083285Phospho.ELM 6.0
685Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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There is no record for ARHGAP35



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