Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

4057

Name

LTF

Synonymous

GIG12|HLF2|LF;lactotransferrin;LTF;lactotransferrin

Definition

growth-inhibiting protein 12|neutrophil lactoferrin|talalactoferrin

Position

3p21.31

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

lactoferrin(h) --> MMP1(h) (DNA binding; transactivation).
lactoferrin(h) --> SKP1A(h) (DNA binding; transactivation).
LTF(h) --> lactoferrin(h) (expression).
SGK-1(h) + lactoferrin(h) <==> SGK-1(h):lactoferrin(h) (binding)
LTF(h) --> lactoferrin(h) (expression).
factor H(h) --> lactoferrin(h) (increase of secretion)

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

156N-linked (GlcNAc...).Swiss-Prot 53.0
497N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr3

Promoter: 46480899 - 46482899Agilent_014791

chr3

Promoter: 46480899 - 46482899GSE27584

chr3

Promoter: 46480899 - 46482899Agilent_014791_44K


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