|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4292 |
Name | MLH1 |
Synonymous | COCA2|FCC2|HNPCC|HNPCC2|hMLH1;mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli);MLH1;mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) |
Definition | DNA mismatch repair protein Mlh1|mutL protein homolog 1 |
Position | 3p21.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
MLH1(h) --Caspase-3(h)--> MLH1-p45(h) + MLH1-p40(h) (processing) | MSH2(h) + MLH1(h) <==> MSH2(h):MLH1(h) (binding) | PMS2(h) + MLH1(h) <==> PMS2(h):MLH1(h) (binding) | PMS2(h) + MLH1(h) + MSH2(h) <==> PMS2(h):MLH1(h):MSH2(h) (binding) | BARD1(h) + BRCA2(h) + brca1(h) + Bach1(h) + MLH1(h) + tubulin(h) + CtIP(h) <==> BARD1(h):BRCA2(h):brca1(h):Bach1(h):MLH1(h):tubulin(h):CtIP(h) (binding) | MLH1(h) + TOP2BP1(h) + Bach1(h) + brca1(h) <==> MLH1(h):TOP2BP1(h):Bach1(h):brca1(h) (binding) | RFC4(h) + RFC2(h) + MLH1(h) + MSH2(h) + RECC1(h) + BLM(h) + ATM(h) + brca1(h) + GTBP(h) <==> RFC4(h):RFC2(h):MLH1(h):MSH2(h):RECC1(h):BLM(h):ATM(h):brca1(h):GTBP(h) (binding) | MLH1(h) + RECC1(h) <==> MLH1(h):RECC1(h) (binding) | GTBP(h) + MLH1(h) <==> GTBP(h):MLH1(h) (binding) | BLM(h) + MLH1(h) <==> BLM(h):MLH1(h) (binding) | Rad50(h) + MLH1(h) <==> Rad50(h):MLH1(h) (binding) | ATM(h) + MLH1(h) <==> ATM(h):MLH1(h) (binding) | beta-adaptin 2(h) + MLH1(h) <==> beta-adaptin 2(h):MLH1(h) (binding) | MLH1(h) + ZC3HDC11A(h) <==> MLH1(h):ZC3HDC11A(h) (binding) | MLH1(h) + Rnf37(h) <==> MLH1(h):Rnf37(h) (binding) | MLH1(h) + TRIM29(h) <==> MLH1(h):TRIM29(h) (binding) | MLH1(h) + Willin(h) <==> MLH1(h):Willin(h) (binding) | MLH1(h) --> MLH1(h) (expression). | MLH1(h) --> MLH1(h) (expression). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
There is no record for MLH1 |
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr3 |
Promoter: 37008483 - 37010483 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 37008483 - 37010483 | GSE27584 |
chr3 |
Promoter: 37008483 - 37010483 | Agilent_014791_44K |
chr3 |
Promoter: 37008483 - 37010483 | Agilent_014791 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:21426665 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:21796503 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11496321 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11306456 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12448005 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12695555 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12692837 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11422806 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14556664 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12746473 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11413518 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10418831 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15616773 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12588445 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10861474 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12763209 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16108828 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15991278 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16475210 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11872960 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10070967 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14742272 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11146446 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16075282 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10495421 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12163364 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12964042 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15831994 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11870538 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16163424 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10585582 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12384516 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15735977 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15069683 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15942635 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10980110 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11140703 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14675710 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15526363 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15386372 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17339237 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15760919 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17183069 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15122305 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12000733 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10987299 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15856472 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16033773 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11341745 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16850502 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17372756 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10468602 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12461746 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11870540 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16436636 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16015629 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17189406 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16820091 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12833454 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12569385 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11601928 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15476557 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14508843 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11729109 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17378912 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16336454 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12004219 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17276933 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10922385 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10793088 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12203784 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14734469 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15294875 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10999752 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15297202 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:9811473 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12700670 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16928264 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16701802 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16323174 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16343186 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10072435 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12079302 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14760069 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16557577 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12796396 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10550333 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16303245 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16773633 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15240532 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16532039 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10327053 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11753956 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15328194 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12974095 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:10766168 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12584167 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14501508 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14668721 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16256791 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16724696 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16764763 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15498213 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15467712 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15471559 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15915369 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12730870 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15635575 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:17219447 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16166431 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:11786399 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16858686 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15172987 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15543763 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:14527906 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16699861 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15746058 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16983315 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16258501 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15551306 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16242928 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12124340 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:15309527 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12632081 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12672028 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16619216 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:12841866 |
chr3 |
Promoter: 37008483 - 37010483 | PMID:16309235 |