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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5080 |
Name | PAX6 |
Synonymous | AN|AN2|D11S812E|MGDA|WAGR;paired box 6;PAX6;paired box 6 |
Definition | aniridia type II protein|oculorhombin|paired box homeotic gene-6|paired box protein Pax-6 |
Position | 11p13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
pax6-isoform1(h) --> QOR(CAV) (DNA binding). | mDia1(m) + pax6-isoform1(h) <==> mDia1(m):pax6-isoform1(h) (binding) | pax6-isoform1(h) --> SIX3(h) (transactivation) | pax6-isoform1(h) + importin-13(h) <==> pax6-isoform1(h):importin-13(h) (binding) | PAX6(h) --> pax6-isoform1(h) (expression). | pax6-isoform5a(h) --> SMARCA4(h) (DNA binding). | pax6-isoform5a(h) --> Itga5(h) (DNA binding). | pax6-isoform5a(h) --> Itgb1(h) (DNA binding). | pax6-isoform5a(h) --/ Palm(m) (transrepression) | pax6-isoform5a(h) --/ Ehbp1l1(m) (transrepression) | pax6-isoform5a(h) --/ Mocs3(m) (transrepression) | pax6-isoform5a(h) --/ ETV6(m) (transrepression) | pax6-isoform5a(h) --/ Cpsf1(m) (transrepression) | pax6-isoform5a(h) --/ Paralemmin(m) (decrease of abundance) | PAX6(h) --> pax6-isoform5a(h) (expression). | pax6(h) + AP-2alpha(h) <==> pax6(h):AP-2alpha(h) (binding) | pax6(h) --> SMARCA4(h) (DNA binding). | pax6(h) --> Itga5(h) (DNA binding). | pax6(h) --> Itgb1(h) (DNA binding). | pax6(h) + importin-13(h) <==> pax6(h):importin-13(h) (binding) | pax6(h) --> MET(h) (DNA binding; transactivation). | pax6(h) --> Atoh1(m) (DNA binding). | pax6(h) --> Atoh7(m) (DNA binding). | pax6(h) --> ITGA4(h) (DNA binding; transactivation). | PAX6(h) --> pax6(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for PAX6 |
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 31788934 - 31790934 | Agilent_014791 |
chr11 |
Promoter: 31788955 - 31790955 | Agilent_014791 |
chr11 |
Promoter: 31788934 - 31790934 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 31788955 - 31790955 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 31788934 - 31790934 | GSE27584 |
chr11 |
Promoter: 31788955 - 31790955 | GSE27584 |
chr11 |
Promoter: 31788934 - 31790934 | Agilent_014791_44K |
chr11 |
Promoter: 31788934 - 31790934 | PMID:11584062 |
chr11 |
Promoter: 31788955 - 31790955 | PMID:11584062 |
chr11 |
Promoter: 31788934 - 31790934 | PMID:16367923 |
chr11 |
Promoter: 31788955 - 31790955 | PMID:16367923 |