Basic Information
Gene ID	5584
Name	PRKCI
Synonymous	DXS1179E\|PKCI\|nPKC-iota;protein kinase C, iota;PRKCI;protein kinase C, iota
Definition	PRKC-lambda/iota\|aPKC-lambda/iota\|atypical protein kinase C-lambda/iota\|protein kinase C iota type
Position	3q26.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database
PKCiota(h) + L-selectin(h) <==> PKCiota(h):L-selectin(h) (binding)
PKCiota(h) + Pard6a(h) <==> PKCiota(h):Pard6a(h) (binding)
PP2A(h) + PKCiota(h) <==> PP2A(h):PKCiota(h) (binding)
PRKCI(h) --> PKCiota(h) (expression).
L-selectin(h) + ATP --PKCiota(h)--> L-selectin(h){pS} + ADP (phosphorylation)
bad(h) + 3 ATP --PKCiota(h)--> bad(h){pS75}{pS99}{pS118} + 3 ADP (phosphorylation)
PRKCI(h) --> PKCiota(h) (expression).
IRAK1(m.s.) + ATP --PKCiota(h)--> IRAK1(m.s.){pT66} + ADP (phosphorylation)

Location (AA)	PTM type	Literature	Database
403	Phosphothreonine.		Swiss-Prot 53.0
555	Phosphothreonine.		Swiss-Prot 53.0
271	Phosphotyrosine (Src)	11713277	Phospho.ELM 6.0
256	Phosphotyrosine (Src)	11713277	Phospho.ELM 6.0
325	Phosphotyrosine (Src)	11713277	Phospho.ELM 6.0
403	Phosphothreonine	15314172	Phospho.ELM 6.0