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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 6597 |
Name | SMARCA4 |
Synonymous | BAF190|BRG1|RTPS2|SNF2|SNF2-BETA|SNF2L4|SNF2LB|SWI2|hSNF2b;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4;SMARCA4;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
Definition | ATP-dependent helicase SMARCA4|BAF190A|BRG1-associated factor 190A|BRM/SWI2-related gene 1|SNF2-like 4|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4|brahma protein-like 1|global transcription activator homol |
Position | 19p13.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
BRG1(h) + hdac2(h) + RbAp48(h) + BAF155(h) + BAF60A(h) + sin3a(h) <==> BRG1(h):hdac2(h):RbAp48(h):BAF155(h):BAF60A(h):sin3a(h) (binding) | sin3a(h) + BRG1(h) <==> sin3a(h):BRG1(h) (binding) | AhR(h) + BRG1(h) <==> AhR(h):BRG1(h) (binding) | BRG1(h) + p53(h) <==> BRG1(h):p53(h) (binding) | BAF47(h) + BAF155(h) + BRG1(h) + p53(h) <==> BAF47(h):BAF155(h):BRG1(h):p53(h) (binding) | BRG1(h) + LKB1(m) <==> BRG1(h):LKB1(m) (binding) | BRG1(h) + LKB1(h) <==> BRG1(h):LKB1(h) (binding) | BRG1(h) + ER-alpha(h) <==> BRG1(h):ER-alpha(h) (binding) | BRG1(h) + BAF60c2(h) + BAF60c1(h) + PPARgamma(h) <==> BRG1(h):BAF60c2(h):BAF60c1(h):PPARgamma(h) (binding) | BAF60(h) + BRG1(h) + BAF170(h) + BAF53a(h) + BAF57(h) + BAF47(m.s.) <==> BAF60(h):BRG1(h):BAF170(h):BAF53a(h):BAF57(h):BAF47(m.s.) (binding) | BRG1(h) + AR-isoform1(h) <==> BRG1(h):AR-isoform1(h) (binding) | BRG1(h) + C/EBPalpha(m.s.) <==> BRG1(h):C/EBPalpha(m.s.) (binding) | BRG1(h) + c-Ets-2(h) <==> BRG1(h):c-Ets-2(h) (binding) | BRG1(h) + PRP4K(h) <==> BRG1(h):PRP4K(h) (binding) | BRG1(h) + PRP4K(h) <==> BRG1(h):PRP4K(h) (binding) | PRP4K(h){p} + BRG1(h) <==> PRP4K(h){p}:BRG1(h) (binding) | BRG1(h) + ATP --PRP4K(h)--> BRG1(h){p} + ADP (phosphorylation) | NCOR1(h) + BRG1(h) + Prp6(h) <==> NCOR1(h):BRG1(h):Prp6(h) (binding) | SMRT(h) + Prp6(h) + PRP4K(h) + BRG1(h) <==> SMRT(h):Prp6(h):PRP4K(h):BRG1(h) (binding) | BRG1(h) + BAF250(h) <==> BRG1(h):BAF250(h) (binding) | BRG1(h) + ARID1B(h) <==> BRG1(h):ARID1B(h) (binding) | BRG1(h) --> HMOX1(h) (transactivation) | Nrf2(m) + BRG1(h) <==> BRG1(h):Nrf2(m) (binding) | c-Myc(h) + BRG1(h) <==> c-Myc(h):BRG1(h) (binding) | BAF47(h) + BAF155(h) + BAF170(h) + Brm(h) + BRG1(h) + MCPH1(m.s.) <==> BAF47(h):BAF155(h):BAF170(h):Brm(h):BRG1(h):MCPH1(m.s.) (binding) | BRG1(h) + Brm(h) + MCT(h) <==> BRG1(h):Brm(h):MCT(h) (binding) | BAF47(h) + Brm(h) + BRG1(h) + BAF155(h) + BAF170(h) <==> BAF47(h):Brm(h):BRG1(h):BAF155(h):BAF170(h) (binding) | SMARCA4(h) --> BRG1(h) (expression). | BRG1(h) + LAP*-NF-M(c) <==> BRG1(h):LAP*-NF-M(c) (binding) | BRG1(h) + Zimp7(h) <==> BRG1(h):Zimp7(h) (binding) | BRG1(h) + BAF250(h) <==> BRG1(h):BAF250(h) (binding) | BRG1(h) + ARID1B(h) <==> BRG1(h):ARID1B(h) (binding) | SMARCA4(h) --> BRG1(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
11 | Phosphothreonine. | Swiss-Prot 53.0 | 655 | Phosphoserine. | Swiss-Prot 53.0 | 657 | Phosphoserine. | Swiss-Prot 53.0 | 660 | Phosphoserine. | Swiss-Prot 53.0 | 662 | Phosphoserine. | Swiss-Prot 53.0 | 695 | Phosphoserine. | Swiss-Prot 53.0 | 1382 | Phosphoserine. | Swiss-Prot 53.0 | 1452 | Phosphoserine. | Swiss-Prot 53.0 | 695 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1382 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
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chr19 |
Promoter: 10931106 - 10933106 | Agilent_014791 |
chr19 |
Promoter: 10931106 - 10933106 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 10931106 - 10933106 | GSE27584 |
chr19 |
Promoter: 10931106 - 10933106 | Agilent_014791_44K |
chr19 |
Promoter: 10931106 - 10933106 | Agilent_014791 |