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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6672 |
Name | SP100 |
Synonymous | lysp100b;SP100 nuclear antigen;SP100;SP100 nuclear antigen |
Definition | SP100-HMG nuclear autoantigen|nuclear autoantigen Sp-100|nuclear dot-associated Sp100 protein|speckled 100 kDa |
Position | 2q37.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
Sp100(h) + DRI1(m) <==> DRI1(m):Sp100(h) (binding) | c-Ets-1(h) + Sp100(h) <==> c-Ets-1(h):Sp100(h) (binding) | Sp100(h) + sumo1(h) --> Sp100(h){sumo} (sumoylation) | Sp100(h) --> Sp100(h) (translocation) | Sp100(h) + SUMO2(h) --> Sp100(h){sumo2} (sumoylation) | Sp100(h) + sumo1(h) <==> Sp100(h):sumo1(h) (binding) | Sp100(h) --> Sp100(h) (expression). | Sp100(h) --> Sp100(h) (translocation) | IFNalpha2b(h) --> Sp100(h) (increase of abundance) | Sp100(h) --> Sp100-HMG(h) (expression). | Sp100-A(h) + c-Ets-1(h) <==> Sp100-A(h):c-Ets-1(h) (binding) | Sp100(h) --> Sp100-A(h) (expression). | Sp100(h) --> Sp100-B(h) (expression). | Sp100(h) --> Sp100-C(h) (expression). | SpAlt-C(h) + sumo1(h) --> SpAlt-C(h){sumo} (sumoylation) | Sp100(h) --> SpAlt-C(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
18 | Phosphoserine. | Swiss-Prot 53.0 | 157 | Phosphoserine. | Swiss-Prot 53.0 | 327 | Phosphoserine. | Swiss-Prot 53.0 | 328 | Phosphoserine. | Swiss-Prot 53.0 | 331 | Phosphoserine. | Swiss-Prot 53.0 | 334 | Phosphoserine. | Swiss-Prot 53.0 | 335 | Phosphothreonine. | Swiss-Prot 53.0 | 407 | Phosphoserine. | Swiss-Prot 53.0 | 409 | Phosphoserine. | Swiss-Prot 53.0 | 410 | Phosphoserine. | Swiss-Prot 53.0 | 451 | Phosphoserine. | Swiss-Prot 53.0 | 452 | Phosphoserine. | Swiss-Prot 53.0 | 453 | Phosphoserine. | Swiss-Prot 53.0 | 456 | Phosphoserine. | Swiss-Prot 53.0 | 459 | Phosphoserine. | Swiss-Prot 53.0 | 297 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO)(Probable). | Swiss-Prot 53.0 | 157 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 407 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 409 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 410 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 18 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 327 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 328 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 331 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 334 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 335 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 451 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 452 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 453 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 456 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 459 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 230987615 - 230989615 | GSE27584 |
chr2 |
Promoter: 230987615 - 230989615 | GSE27584 |