Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

8451

Name

CUL4A

Synonymous

-;cullin 4A;CUL4A;cullin 4A

Definition

CUL-4A|cullin-4A

Position

13q34

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

CUL4A(h) + Nedd8(h) --> CUL4A(h){nedd} (neddylation)
Roc1(h) + CUL4A(h) + DDB-2(h) + DDB1(h) <==> Roc1(h):CUL4A(h):DDB-2(h):DDB1(h) (binding)
CUL4A(h) --> CUL4A(h) (expression).
DDB1(h) + CUL4A-isoform2(h) <==> DDB1(h):CUL4A-isoform2(h) (binding)
CRBN-isoform1(h) + CUL4A-isoform2(h) <==> CRBN-isoform1(h):CUL4A-isoform2(h) (binding)
CUL4A-isoform2(h) + COPS8(h) <==> CUL4A-isoform2(h):COPS8(h) (binding)
DDB-2-isoform1(h) + CUL4A-isoform2(h) <==> DDB-2-isoform1(h):CUL4A-isoform2(h) (binding)
COPS4(h) + CUL4A-isoform2(h) <==> COPS4(h):CUL4A-isoform2(h) (binding)
CUL4A-isoform2(h) + Tip120a(h) <==> CUL4A-isoform2(h):Tip120a(h) (binding)
VPRBP(h) + CUL4A-isoform2(h) <==> VPRBP(h):CUL4A-isoform2(h) (binding)
NRIP(h) + CUL4A-isoform2(h) <==> NRIP(h):CUL4A-isoform2(h) (binding)
WDR23-isoform1(h) + CUL4A-isoform2(h) <==> WDR23-isoform1(h):CUL4A-isoform2(h) (binding)
CUL4A-isoform2(h) + C19orf58(h) <==> CUL4A-isoform2(h):C19orf58(h) (binding)
C4orf30(h) + CUL4A-isoform2(h) <==> C4orf30(h):CUL4A-isoform2(h) (binding)
LULL1(h) + CUL4A-isoform2(h) <==> LULL1(h):CUL4A-isoform2(h) (binding)
WDTC-1(h) + CUL4A-isoform2(h) <==> WDTC-1(h):CUL4A-isoform2(h) (binding)
CSA(h) + CUL4A-isoform2(h) <==> CSA(h):CUL4A-isoform2(h) (binding)
wdr42a(h) + CUL4A-isoform2(h) <==> wdr42a(h):CUL4A-isoform2(h) (binding)
hist1h1e(h) + CUL4A-isoform2(h) <==> hist1h1e(h):CUL4A-isoform2(h) (binding)
WDR21A(h) + CUL4A-isoform2(h) <==> WDR21A(h):CUL4A-isoform2(h) (binding)
TRPC4AP(h) + CUL4A-isoform2(h) <==> TRPC4AP(h):CUL4A-isoform2(h) (binding)
Nedd8(h) + CUL4A-isoform2(h) <==> Nedd8(h):CUL4A-isoform2(h) (binding)
COPS7A(h) + CUL4A-isoform2(h) <==> COPS7A(h):CUL4A-isoform2(h) (binding)
COPS2-isoform1(h) + CUL4A-isoform2(h) <==> COPS2-isoform1(h):CUL4A-isoform2(h) (binding)
COPS6(h) + CUL4A-isoform2(h) <==> COPS6(h):CUL4A-isoform2(h) (binding)
WDR32(h) + CUL4A-isoform2(h) <==> WDR32(h):CUL4A-isoform2(h) (binding)
COPS7B(h) + CUL4A-isoform2(h) <==> COPS7B(h):CUL4A-isoform2(h) (binding)
DTL(h) + CUL4A-isoform2(h) <==> DTL(h):CUL4A-isoform2(h) (binding)
JAB1(h) + CUL4A-isoform2(h) <==> JAB1(h):CUL4A-isoform2(h) (binding)
PHIP(h) + CUL4A-isoform2(h) <==> PHIP(h):CUL4A-isoform2(h) (binding)
COPS3(h) + CUL4A-isoform2(h) <==> COPS3(h):CUL4A-isoform2(h) (binding)
WDR40A(h) + CUL4A-isoform2(h) <==> WDR40A(h):CUL4A-isoform2(h) (binding)
WDR22(h) + CUL4A-isoform2(h) <==> WDR22(h):CUL4A-isoform2(h) (binding)
WDR9-isoform1(h) + CUL4A-isoform2(h) <==> WDR9-isoform1(h):CUL4A-isoform2(h) (binding)
CUL4A(h) --> CUL4A-isoform2(h) (expression).
CUL4A(h) --> CUL4A-isoform1(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

705Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in NEDD8) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr13

Promoter: 112910432 - 112912432Agilent_014791

chr13

Promoter: 112910432 - 112912432GSE27584

chr13

Promoter: 112909587 - 112911587GSE27584

chr13

Promoter: 112910432 - 112912432Agilent_014791_44K

chr13

Promoter: 112909587 - 112911587Agilent_014791_44K


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