Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

889

Name

KRIT1

Synonymous

CAM|CCM1;KRIT1, ankyrin repeat containing;KRIT1;KRIT1, ankyrin repeat containing

Definition

ankyrin repeat-containing protein Krit1|cerebral cavernous malformations 1 protein|krev interaction trapped 1|krev interaction trapped protein 1

Position

7q21.2

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

KRIT1(h) --> KRIT1-isoform1(h) (expression).
KRIT1(h) + MEKK3(m.s.) + CCM2(h) <==> KRIT1(h):MEKK3(m.s.):CCM2(h) (binding)
KRIT1(h) + CCM2(h) <==> KRIT1(h):CCM2(h) (binding)
KRIT1(h) --> KRIT1(h) (translocation)
KRIT1(h) + CCM2(h) + ICAP-1alpha(h) <==> KRIT1(h):CCM2(h):ICAP-1alpha(h) (binding)
KRIT1(h) --> KRIT1(h) (expression).
KRIT1(h) --> KRIT1(h) (translocation)
KRIT1(h) --> KRIT1-isoform2(h) (expression).

Post Transcriptional Modification From dbPTM

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There is no record for KRIT1

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr7

Promoter: 91712664 - 91714664Agilent_014791

chr7

Promoter: 91712850 - 91714850Agilent_014791

chr7

Promoter: 91712664 - 91714664GSE27584

chr7

Promoter: 91712850 - 91714850GSE27584

chr7

Promoter: 91712850 - 91714850GSE27584

chr7

Promoter: 91712664 - 91714664GSE27584

chr7

Promoter: 91712648 - 91714648GSE27584

chr7

Promoter: 91712664 - 91714664Agilent_014791_44K


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