Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30079703HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TVIS30034268HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TCGA Plot Options
Drug Information
GenePLA2G1B
DrugBank IDDB00591
Drug NameFluocinolone acetonide
Target IDBE0003997
UniProt IDP04054
Regulation Typeinhibitor
PubMed IDs6877258; 3133247
CitationsEmerit I, Levy A, Cerutti P: Suppression of tumor promoter phorbolmyristate acetate-induced chromosome breakage by antioxidants and inhibitors of arachidonic acid metabolism. Mutat Res. 1983 Aug;110(2):327-35. doi: 10.1016/0027-5107(83)90149-5.@@Kaszkin M, Espe U, Furstenberger G, Kinzel V: Dual effect of the phorbol ester TPA on arachidonic acid release from HeLa cells. FEBS Lett. 1988 Jun 20;233(2):244-8. doi: 10.1016/0014-5793(88)80435-6.
GroupsApproved; Investigational; Vet_approved
Direct Classification21-hydroxysteroids
SMILES[H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO
Pathways
PharmGKBPA164754912
ChEMBLCHEMBL989