Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30079703HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TVIS30034268HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TCGA Plot Options
Drug Information
GenePLA2G1B
DrugBank IDDB04552
Drug NameNiflumic acid
Target IDBE0003997
UniProt IDP04054
Regulation Typeinhibitor
PubMed IDs16301791; 10592235
CitationsJabeen T, Singh N, Singh RK, Sharma S, Somvanshi RK, Dey S, Singh TP: Non-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1579-86. Epub 2005 Nov 19.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationTrifluoromethylbenzenes
SMILESOC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
Pathways
PharmGKBPA164746749
ChEMBLCHEMBL63323