Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30079703HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TVIS30034268HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TCGA Plot Options
Drug Information
GenePLA2G1B
DrugBank IDDB00972
Drug NameAzelastine
Target IDBE0003997
UniProt IDP04054
Regulation Typeinhibitor
PubMed IDs8630722
CitationsHamasaki Y, Shafigeh M, Yamamoto S, Sato R, Zaitu M, Muro E, Kobayashi I, Ichimaru T, Tasaki H, Miyazaki S: Inhibition of leukotriene synthesis by azelastine. Ann Allergy Asthma Immunol. 1996 May;76(5):469-75. doi: 10.1016/S1081-1206(10)63465-5.
GroupsApproved
Direct ClassificationPhthalazinones
SMILESCN1CCCC(CC1)N1N=C(CC2=CC=C(Cl)C=C2)C2=CC=CC=C2C1=O
PathwaysAzelastine H1-Antihistamine Action
PharmGKBPA448517
ChEMBLCHEMBL639