Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30079703HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TVIS30034268HIVENSG00000170890.14protein_codingPLA2G1BNoNo5319P04054
TCGA Plot Options
Drug Information
GenePLA2G1B
DrugBank IDDB00795
Drug NameSulfasalazine
Target IDBE0003997
UniProt IDP04054
Regulation Typeantagonist
PubMed IDs9256165
CitationsPruzanski W, Stefanski E, Vadas P, Ramamurthy NS: Inhibition of extracellular release of proinflammatory secretory phospholipase A2 (sPLA2) by sulfasalazine: a novel mechanism of anti-inflammatory activity. Biochem Pharmacol. 1997 Jun 15;53(12):1901-7.
GroupsApproved
Direct ClassificationAzobenzenes
SMILESOC(=O)C1=CC(=CC=C1O)N=NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
Pathways
PharmGKBPA451547
ChEMBLCHEMBL421