| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30079703 | HIV | ENSG00000170890.14 | protein_coding | PLA2G1B | No | No | 5319 | P04054 |
| TVIS30034268 | HIV | ENSG00000170890.14 | protein_coding | PLA2G1B | No | No | 5319 | P04054 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLA2G1B |
|---|---|
| DrugBank ID | DB03587 |
| Drug Name | Pyruvaldehyde |
| Target ID | BE0003997 |
| UniProt ID | P04054 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Alpha ketoaldehydes |
| SMILES | CC(=O)C=O |
| Pathways | Leigh Syndrome; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Pyruvate Metabolism; Primary Hyperoxaluria II, PH2; 3-Phosphoglycerate Dehydrogenase Deficiency; Pyruvate Kinase Deficiency; Glycine and Serine Metabolism; Hyperglycinemia, Non-Ketotic; Spermidine and Spermine Biosynthesis; Sarcosinemia; Non-Ketotic Hyperglycinemia; Dimethylglycine Dehydrogenase Deficiency; Pyruvate Dehydrogenase Complex Deficiency; Pyruvaldehyde Degradation; Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) |
| PharmGKB | |
| ChEMBL | CHEMBL170721 |
