| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30017029 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047835 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047836 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047837 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047838 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047839 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020749 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020750 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4A |
|---|---|
| DrugBank ID | DB01954 |
| Drug Name | Rolipram |
| Target ID | BE0009963 |
| UniProt ID | Q08499 |
| Regulation Type | inhibitor |
| PubMed IDs | 22629087 |
| Citations | Shalaby AM, Kamal SM: Effect of rolipram, a phosphodiesterase enzyme type-4 inhibitor, on gamma-amino butyric acid content of the frontal cortex in mice exposed to chronic mild stress. J Pharmacol Pharmacother. 2012 Apr;3(2):132-7. doi: 10.4103/0976-500X.95509. |
| Groups | Investigational |
| Direct Classification | Phenylpyrrolidines |
| SMILES | COC1=C(OC2CCCC2)C=C(C=C1)C1CNC(=O)C1 |
| Pathways | |
| PharmGKB | PA153906323 |
| ChEMBL | CHEMBL63 |
