| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30017029 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047835 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047836 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047837 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047838 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047839 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020749 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020750 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4A |
|---|---|
| DrugBank ID | DB08811 |
| Drug Name | Tofisopam |
| Target ID | BE0001133 |
| UniProt ID | P27815 |
| Regulation Type | inhibitor |
| PubMed IDs | 20967473 |
| Citations | Rundfeldt C, Socala K, Wlaz P: The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. J Neural Transm (Vienna). 2010 Nov;117(11):1319-25. doi: 10.1007/s00702-010-0507-3. Epub 2010 Oct 22. |
| Groups | Experimental |
| Direct Classification | Benzodiazepines |
| SMILES | CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1 |
| Pathways | |
| PharmGKB | PA165958428 |
| ChEMBL | CHEMBL404216 |
