| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30017029 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047835 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047836 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047837 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047838 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS30047839 | HIV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020749 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
| TVIS20020750 | HPV | ENSG00000065989.16 | protein_coding | PDE4A | No | No | 5141 | P27815 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PDE4A |
|---|---|
| DrugBank ID | DB01656 |
| Drug Name | Roflumilast |
| Target ID | BE0009963 |
| UniProt ID | Q08499 |
| Regulation Type | inhibitor |
| PubMed IDs | 20689641 |
| Citations | Giembycz MA, Field SK: Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD. Drug Des Devel Ther. 2010 Jul 21;4:147-58. doi: 10.2147/dddt.s7667. |
| Groups | Approved |
| Direct Classification | Benzamides |
| SMILES | FC(F)OC1=C(OCC2CC2)C=C(C=C1)C(=O)NC1=C(Cl)C=NC=C1Cl |
| Pathways | |
| PharmGKB | PA165948052 |
| ChEMBL | CHEMBL193240 |
