| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20024401 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS20021335 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049649 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049650 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARA |
|---|---|
| DrugBank ID | DB12808 |
| Drug Name | Trifarotene |
| Target ID | BE0000663 |
| UniProt ID | P10276 |
| Regulation Type | agonist |
| PubMed IDs | 29974453 |
| Citations | Aubert J, Piwnica D, Bertino B, Blanchet-Rethore S, Carlavan I, Deret S, Dreno B, Gamboa B, Jomard A, Luzy AP, Mauvais P, Mounier C, Pascau J, Pelisson I, Portal T, Rivier M, Rossio P, Thoreau E, Vial E, Voegel JJ: Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-gamma agonist trifarotene. Br J Dermatol. 2018 Aug;179(2):442-456. doi: 10.1111/bjd.16719. Epub 2018 Jul 4. |
| Groups | Approved; Investigational |
| Direct Classification | M-terphenyls |
| SMILES | CC(C)(C)C1=CC(=CC=C1N1CCCC1)C1=CC(=CC=C1OCCO)C1=CC=C(C=C1)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3707313 |
