| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20024401 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS20021335 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049649 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049650 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARA |
|---|---|
| DrugBank ID | DB00459 |
| Drug Name | Acitretin |
| Target ID | BE0000663 |
| UniProt ID | P10276 |
| Regulation Type | agonist |
| PubMed IDs | 10459139; 9074840; 9153406; 19144697 |
| Citations | Saurat JH: Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment. J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S2-6.@@Orfanos CE, Zouboulis CC, Almond-Roesler B, Geilen CC: Current use and future potential role of retinoids in dermatology. Drugs. 1997 Mar;53(3):358-88.@@Tian K, Norris AW, Lin CL, Li E: The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains. Biochemistry. 1997 May 13;36(19):5669-76.@@Tippmann F, Hundt J, Schneider A, Endres K, Fahrenholz F: Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin. FASEB J. 2009 Jun;23(6):1643-54. doi: 10.1096/fj.08-121392. Epub 2009 Jan 14. |
| Groups | Approved |
| Direct Classification | Retinoids |
| SMILES | COC1=C(C)C(C)=C(C=CC(C)=CC=CC(C)=CC(O)=O)C(C)=C1 |
| Pathways | |
| PharmGKB | PA448039 |
| ChEMBL | CHEMBL1131 |
