| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20024401 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS20021335 | HPV | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049649 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
| TVIS44049650 | HTLV-1 | ENSG00000131759.18 | protein_coding | RARA | No | No | 5914 | A8MUP8 P10276 Q6I9R7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARA |
|---|---|
| DrugBank ID | DB04942 |
| Drug Name | Tamibarotene |
| Target ID | BE0000663 |
| UniProt ID | P10276 |
| Regulation Type | agonist |
| PubMed IDs | 17925887; 15843826; 11752352; 17611697; 15563242 |
| Citations | Miwako I, Kagechika H: Tamibarotene. Drugs Today (Barc). 2007 Aug;43(8):563-8.@@Sanda T, Kuwano T, Nakao S, Iida S, Ishida T, Komatsu H, Shudo K, Kuwano M, Ono M, Ueda R: Antimyeloma effects of a novel synthetic retinoid Am80 (Tamibarotene) through inhibition of angiogenesis. Leukemia. 2005 Jun;19(6):901-9.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Jimi S, Mashima K, Matsumoto T, Hara S, Suzumiya J, Tamura K: RARalpha is a regulatory factor for Am-80-induced cell growth inhibition of hematologic malignant cells. Int J Oncol. 2007 Aug;31(2):397-404.@@Authors unspecified: Tamibarotene: AM 80, retinobenzoic acid, Tamibaro. Drugs R D. 2004;5(6):359-62. |
| Groups | Investigational |
| Direct Classification | Tetralins |
| SMILES | CC1(C)CCC(C)(C)C2=C1C=CC(NC(=O)C1=CC=C(C=C1)C(O)=O)=C2 |
| Pathways | |
| PharmGKB | PA164743464 |
| ChEMBL | CHEMBL25202 |
