| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20056727 | HPV | ENSG00000144852.20 | protein_coding | NR1I2 | No | No | 8856 | O75469 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NR1I2 |
|---|---|
| DrugBank ID | DB00531 |
| Drug Name | Cyclophosphamide |
| Target ID | BE0000956 |
| UniProt ID | O75469 |
| Regulation Type | |
| PubMed IDs | 18839173 |
| Citations | Harmsen S, Meijerman I, Beijnen JH, Schellens JH: Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2009 Jun;64(1):35-43. doi: 10.1007/s00280-008-0842-3. Epub 2008 Oct 7. |
| Groups | Approved; Investigational |
| Direct Classification | Nitrogen mustard compounds |
| SMILES | ClCCN(CCCl)P1(=O)NCCCO1 |
| Pathways | Cyclophosphamide Action Pathway; Cyclophosphamide Metabolism Pathway |
| PharmGKB | PA449165 |
| ChEMBL | CHEMBL88 |
