Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20056727HPVENSG00000144852.20protein_codingNR1I2NoNo8856O75469
TCGA Plot Options
Drug Information
GeneNR1I2
DrugBank IDDB12582
Drug NamePiperine
Target IDBE0000956
UniProt IDO75469
Regulation Type
PubMed IDs23707768
CitationsWang YM, Lin W, Chai SC, Wu J, Ong SS, Schuetz EG, Chen T: Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):96-107. doi: 10.1016/j.taap.2013.05.014. Epub 2013 May 22.
GroupsInvestigational
Direct ClassificationAlkaloids and derivatives
SMILESO=C(C=CC=CC1=CC2=C(OCO2)C=C1)N1CCCCC1
Pathways
PharmGKB
ChEMBLCHEMBL43185