Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20056727HPVENSG00000144852.20protein_codingNR1I2NoNo8856O75469
TCGA Plot Options
Drug Information
GeneNR1I2
DrugBank IDDB00499
Drug NameFlutamide
Target IDBE0000956
UniProt IDO75469
Regulation Type
PubMed IDs18839173
CitationsHarmsen S, Meijerman I, Beijnen JH, Schellens JH: Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2009 Jun;64(1):35-43. doi: 10.1007/s00280-008-0842-3. Epub 2008 Oct 7.
GroupsApproved; Investigational
Direct ClassificationTrifluoromethylbenzenes
SMILESCC(C)C(=O)NC1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F
Pathways
PharmGKBPA449685
ChEMBLCHEMBL806