Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20056727HPVENSG00000144852.20protein_codingNR1I2NoNo8856O75469
TCGA Plot Options
Drug Information
GeneNR1I2
DrugBank IDDB01181
Drug NameIfosfamide
Target IDBE0000956
UniProt IDO75469
Regulation Type
PubMed IDs18839173
CitationsHarmsen S, Meijerman I, Beijnen JH, Schellens JH: Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2009 Jun;64(1):35-43. doi: 10.1007/s00280-008-0842-3. Epub 2008 Oct 7.
GroupsApproved
Direct ClassificationIsofamides
SMILESClCCNP1(=O)OCCCN1CCCl
PathwaysIfosfamide Action Pathway; Ifosfamide Metabolism Pathway
PharmGKBPA449964
ChEMBLCHEMBL1024