| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20064211 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS20064150 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44027967 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44049811 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44035846 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2C |
|---|---|
| DrugBank ID | DB00472 |
| Drug Name | Fluoxetine |
| Target ID | BE0000533 |
| UniProt ID | P28335 |
| Regulation Type | antagonist |
| PubMed IDs | 18083778; 11082448; 9050900 |
| Citations | Chanrion B, Mannoury la Cour C, Gavarini S, Seimandi M, Vincent L, Pujol JF, Bockaert J, Marin P, Millan MJ: Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol. 2008 Mar;73(3):748-57. Epub 2007 Dec 14.@@Cryan JF, Lucki I: Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors. J Pharmacol Exp Ther. 2000 Dec;295(3):1120-6.@@Ni YG, Miledi R: Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac). Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):2036-40. doi: 10.1073/pnas.94.5.2036. |
| Groups | Approved; Vet_approved |
| Direct Classification | Trifluoromethylbenzenes |
| SMILES | CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1 |
| Pathways | Fluoxetine Metabolism Pathway; Fluoxetine Action Pathway |
| PharmGKB | PA449673 |
| ChEMBL | CHEMBL41 |
