| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20064211 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS20064150 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44027967 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44049811 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44035846 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | HTR2C |
|---|---|
| DrugBank ID | DB00540 |
| Drug Name | Nortriptyline |
| Target ID | BE0000533 |
| UniProt ID | P28335 |
| Regulation Type | antagonist |
| PubMed IDs | 8876023; 8131152 |
| Citations | Palvimaki EP, Roth BL, Majasuo H, Laakso A, Kuoppamaki M, Syvalahti E, Hietala J: Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berl). 1996 Aug;126(3):234-40.@@Stahl SM, Hauger RL, Rausch JL, Fleishaker JC, Hubbell-Alberts E: Downregulation of serotonin receptor subtypes by nortriptyline and adinazolam in major depressive disorder: neuroendocrine and platelet markers. Clin Neuropharmacol. 1993;16 Suppl 3:S19-31. |
| Groups | Approved |
| Direct Classification | Dibenzocycloheptenes |
| SMILES | CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA450657 |
| ChEMBL | CHEMBL445 |
