| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20064211 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS20064150 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44027967 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44049811 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44035846 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2C |
|---|---|
| DrugBank ID | DB01242 |
| Drug Name | Clomipramine |
| Target ID | BE0000533 |
| UniProt ID | P28335 |
| Regulation Type | antagonist |
| PubMed IDs | 9862411; 14501155; 1296670 |
| Citations | Sargent PA, Quested DJ, Cowen PJ: Clomipramine enhances the cortisol response to 5-HTP: implications for the therapeutic role of 5-HT2 receptors. Psychopharmacology (Berl). 1998 Nov;140(1):120-2.@@Sugimoto Y, Inoue K, Yamada J: The tricyclic antidepressant clomipramine increases plasma glucose levels of mice. J Pharmacol Sci. 2003 Sep;93(1):74-9.@@Contreras CM, Marvan ML, Munoz-Mendez A, Ramirez-Morales A: Cortical and septal responses to dorsal raphe nucleus stimulation in the rat: long-term clomipramine actions. Bol Estud Med Biol. 1992 Jan-Dec;40(1-4):3-7. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Dibenzazepines |
| SMILES | CN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2 |
| Pathways | Clomipramine Metabolism Pathway |
| PharmGKB | PA449048 |
| ChEMBL | CHEMBL415 |
