| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20064211 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS20064150 | HPV | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44027967 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44049811 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
| TVIS44035846 | HTLV-1 | ENSG00000147246.10 | protein_coding | HTR2C | No | No | 3358 | P28335 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2C |
|---|---|
| DrugBank ID | DB05316 |
| Drug Name | Pimavanserin |
| Target ID | BE0000533 |
| UniProt ID | P28335 |
| Regulation Type | inverse agonist |
| PubMed IDs | 27503570 |
| Citations | Stahl SM: Mechanism of action of pimavanserin in Parkinson's disease psychosis: targeting serotonin 5HT2A and 5HT2C receptors. CNS Spectr. 2016 Aug;21(4):271-5. doi: 10.1017/S1092852916000407. |
| Groups | Approved; Investigational |
| Direct Classification | Phenol ethers |
| SMILES | CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2111101 |