Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20064211HPVENSG00000147246.10protein_codingHTR2CNoNo3358P28335
TVIS20064150HPVENSG00000147246.10protein_codingHTR2CNoNo3358P28335
TVIS44027967HTLV-1ENSG00000147246.10protein_codingHTR2CNoNo3358P28335
TVIS44049811HTLV-1ENSG00000147246.10protein_codingHTR2CNoNo3358P28335
TVIS44035846HTLV-1ENSG00000147246.10protein_codingHTR2CNoNo3358P28335
TCGA Plot Options
Drug Information
GeneHTR2C
DrugBank IDDB05316
Drug NamePimavanserin
Target IDBE0000533
UniProt IDP28335
Regulation Typeinverse agonist
PubMed IDs27503570
CitationsStahl SM: Mechanism of action of pimavanserin in Parkinson's disease psychosis: targeting serotonin 5HT2A and 5HT2C receptors. CNS Spectr. 2016 Aug;21(4):271-5. doi: 10.1017/S1092852916000407.
GroupsApproved; Investigational
Direct ClassificationPhenol ethers
SMILESCC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL2111101