Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039946HBVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS10040735HBVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS20001818HPVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS20010059HPVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS44025444HTLV-1ENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS44016388HTLV-1ENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TCGA Plot Options
Drug Information
GeneSLC6A3
DrugBank IDDB00830
Drug NamePhenmetrazine
Target IDBE0000647
UniProt IDQ01959
Regulation Typeinhibitor
PubMed IDs17139284; 17016423; 12106802; 17017961
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Rothman RB, Katsnelson M, Vu N, Partilla JS, Dersch CM, Blough BE, Baumann MH: Interaction of the anorectic medication, phendimetrazine, and its metabolites with monoamine transporters in rat brain. Eur J Pharmacol. 2002 Jun 28;447(1):51-7.@@Rothman RB, Baumann MH: Therapeutic potential of monoamine transporter substrates. Curr Top Med Chem. 2006;6(17):1845-59.
GroupsApproved; Illicit
Direct ClassificationPhenylmorpholines
SMILESCC1NCCOC1C1=CC=CC=C1
Pathways
PharmGKBPA164747188
ChEMBLCHEMBL1201208