| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039946 | HBV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS10040735 | HBV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS20001818 | HPV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS20010059 | HPV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS44025444 | HTLV-1 | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS44016388 | HTLV-1 | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC6A3 |
|---|---|
| DrugBank ID | DB01576 |
| Drug Name | Dextroamphetamine |
| Target ID | BE0000647 |
| UniProt ID | Q01959 |
| Regulation Type | negative modulator |
| PubMed IDs | 16122767; 7869099; 19244097 |
| Citations | Zhen J, Chen N, Reith ME: Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates. Neuropharmacology. 2005 Nov;49(6):769-79. Epub 2005 Aug 24.@@Kuczenski R, Segal DS, Cho AK, Melega W: Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J Neurosci. 1995 Feb;15(2):1308-17.@@Rothman RB, Dersch CM, Ananthan S, Partilla JS: Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release. J Pharmacol Exp Ther. 2009 May;329(2):718-28. doi: 10.1124/jpet.108.149088. Epub 2009 Feb 24. |
| Groups | Approved; Illicit |
| Direct Classification | Amphetamines and derivatives |
| SMILES | C[C@H](N)CC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA449269 |
| ChEMBL | CHEMBL612 |
